2. Gene
  3. GORASP2 - golgi reassembly stacking protein 2 Gene

GORASP2 - golgi reassembly stacking protein 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as p59; GRS2; GOLPH6; GRASP55

Gene ID: 26003 | Gene type: protein coding

About GORASP2

Cytogenetic location: 2q31.1 Genomic coordinates (GRCh38): 2:170,928,477-170,967,130 (from NCBI)

This gene has 11 transcripts (splice variants), 268 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 25.6), placenta (RPKM 23.9) and 25 other tissues.

Summary

This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during Apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

GORASP2 Products(2)

mRNA Protein Name
NM_001201428.2 NP_001188357.1 Golgi reassembly-stacking protein 2 isoform 2
NM_015530.5 NP_056345.3 Golgi reassembly-stacking protein 2 isoform 1

GORASP2 Protein Structure

GRASP55_65

GRASP55_65: GRASP55/65 PDZ-like domain (69 - 204)

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  • 452 a.a.
Protein Preferred Names Protein Names

Golgi reassembly-stacking protein 2

golgi phosphoprotein 6

Related Diseases

Diseases Alias
Smith-Mccort Dysplasia 1

Smith-Mccort Dysplasia

SMC1

Smc

Smith Mccort Dysplasia

Smith-Mccort Dwarfism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P0227 SHU 9119 99.95% Unkown
HY-RS05602 GORASP2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GORASP2 MGD MGI:2135962
Macaca mulatta GORASP2 VGNC VGNC:72957
Felis catus GORASP2 VGNC VGNC:62648
Bos taurus GORASP2 VGNC VGNC:29499
Rattus norvegicus GORASP2 RGD RGD:619911
Canis familiaris GORASP2 VGNC VGNC:41352