FDCSP - follicular dendritic cell secreted protein Gene

Homo sapiens

Also known as C4orf7; FDC-SP

Gene ID: 260436 | Gene type: protein coding

About FDCSP

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:70,226,124-70,235,252 (from NCBI)

This gene has 1 transcript (splice variant) and 44 orthologues. Biased expression in salivary gland (RPKM 447.2), lymph node (RPKM 235.7) and 1 other tissue.

Summary

This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting Cancer cell migration and invasion. [provided by RefSeq, Dec 2011]

FDCSP Products(1)

mRNA	Protein	Name
NM_152997.4	NP_694542.1	follicular dendritic cell secreted peptide precursor

FDCSP Protein Structure

FDC-SP

0
85 a.a.

Protein Preferred Names

Protein Names

follicular dendritic cell secreted peptide

FDC secreted protein

Related Diseases

Diseases

Alias

Follicular Dendritic Cell Sarcoma

Dendritic Cell Sarcoma	Dendritic Cell Sarcoma, Follicular
Follicular Dendritic Cell Tumour	Dendritic Cell Sarcoma, Interdigitating
Dendritic Cell Sarcoma, Not Otherwise Specified

Epidermolysis Bullosa, Junctional 5b, With Pyloric Atresia

Junctional Epidermolysis Bullosa With Pyloric Atresia	Carmi Syndrome
Epidermolysis Bullosa, Junctional, With Pyloric Atresia	Jeb-Pa
JEB5B	Epidermolysis Bullosa Junctionalis With Pyloric Atresia
Aplasia Cutis Congenita With Gastrointestinal Atresia	Epidermolysis Bullosa, Junctional, With Pyloric Atresia And Aplasia Cutis Congenita
Eb-Pa-Acc	Junctional Epidermolysis Bullosa-Pyloric Atresia Syndrome
Jeb With Pyloric Atresia	Epidermolysis Bullosa Letalis, With Pyloric Atresia
Pa-Jeb	Epidermolysis Bullosa With Pyloric Atresia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04851	FDCSP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	FDCSP	RGD	RGD:1359468

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