SERBP1 - SERPINE1 mRNA binding protein 1 Gene

Homo sapiens

Also known as CGI-55; CHD3IP; HABP4L; PAIRBP1; PAI-RBP1

Gene ID: 26135 | Gene type: protein coding

About SERBP1

Cytogenetic location: 1p31.3 Genomic coordinates (GRCh38): 1:67,407,810-67,430,402 (from NCBI)

This gene has 8 transcripts (splice variants), 282 orthologues and 1 paralogue. Ubiquitous expression in esophagus (RPKM 40.3), thyroid (RPKM 34.9) and 25 other tissues.

Summary

Enables SUMO binding activity; mRNA 3'-UTR binding activity; and ribosome binding activity. Involved in PML body organization. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SERBP1 Products(4)

mRNA	Protein	Name
NM_001018067.2	NP_001018077.1	plasminogen activator inhibitor 1 RNA-binding protein isoform 1
NM_001018068.2	NP_001018078.1	plasminogen activator inhibitor 1 RNA-binding protein isoform 2
NM_001018069.2	NP_001018079.1	plasminogen activator inhibitor 1 RNA-binding protein isoform 3
NM_015640.4	NP_056455.3	plasminogen activator inhibitor 1 RNA-binding protein isoform 4

SERBP1 Protein Structure

HABP4_PAI-RBP1

0
100
200
300
408 a.a.

Protein Preferred Names

Protein Names

plasminogen activator inhibitor 1 RNA-binding protein

PAI-1 mRNA binding protein

Related Diseases

Diseases

Alias

Ovarian Cancer

Ovarian Carcinoma	Ovarian Neoplasm
Malignant Tumour Of Ovary	Cancer Of The Ovary
Epithelial Ovarian Cancer	Neoplasm Of Ovary
Ovarian Neoplasms	Ovarian Cancers
Malignant Neoplasm Of Ovary	Primary Malignant Neoplasm Of Ovary
Ovarian Cancer, Somatic	Malignant Ovarian Tumor
Ovary Neoplasm	Primary Ovarian Cancer
Tumor Of The Ovary	Malignant Neoplasm Of The Ovary
Malignant Tumor Of The Ovary	Ovarian Malignant Tumor
OC	Ovarian Carcinomas
Cancer, Ovarian	Cancer Of Ovary
Ovary Cancer	Ca Ovary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12687	SERBP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SERBP1	VGNC	VGNC:46018
Felis catus	SERBP1	VGNC	VGNC:65016
Bos taurus	SERBP1	VGNC	VGNC:34461
Mus musculus	SERBP1	MGD	MGI:1914120
Macaca mulatta	SERBP1	VGNC	VGNC:81566
Rattus norvegicus	SERBP1	RGD	RGD:619907

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