2. Gene
  3. PHF19 - PHD finger protein 19 Gene

PHF19 - PHD finger protein 19 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PCL3; MTF2L1; TDRD19B

Gene ID: 26147 | Gene type: protein coding

About PHF19

Cytogenetic location: 9q33.2 Genomic coordinates (GRCh38): 9:120,855,651-120,904,128 (from NCBI)

This gene has 14 transcripts (splice variants), 213 orthologues and 2 paralogues. Ubiquitous expression in lymph node (RPKM 8.7), ovary (RPKM 6.6) and 24 other tissues.

Summary

Enables methylated histone binding activity. Involved in positive regulation of histone H3-K27 methylation. Colocalizes with ESC/E(Z) complex. [provided by Alliance of Genome Resources, Apr 2022]

PHF19 Products(5)

mRNA Protein Name
NM_001009936.3 NP_001009936.1 PHD finger protein 19 isoform b
NM_001286840.1 NP_001273769.1 PHD finger protein 19 isoform c
NM_001286842.1 NP_001273771.1 PHD finger protein 19 isoform d
NM_001286843.2 NP_001273772.1 PHD finger protein 19 isoform e
NM_015651.3 NP_056466.1 PHD finger protein 19 isoform a

PHF19 Protein Structure

PHD

PHD: PHD-finger (99 - 149)

Mtf2_C

Mtf2_C: Polycomb-like MTF2 factor 2 (530 - 578)

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  • 500
  • 580 a.a.
Protein Preferred Names Protein Names

PHD finger protein 19

polycomb like 3

Related Diseases

Diseases Alias
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
Rheumatoid Arthritis

RA

Arthritis, Rheumatoid

Rheumatoid Arthritis, Susceptibility To

Arthritis Or Polyarthritis, Rheumatic

Atrophic Arthritis

Rheumatism Arthritis

Rheumatoid Polyarthritis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10419 PHF19 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PHF19 VGNC VGNC:64140
Bos taurus PHF19 VGNC VGNC:32817
Mus musculus PHF19 MGD MGI:1921266
Macaca mulatta PHF19 VGNC VGNC:75857
Canis familiaris PHF19 VGNC VGNC:59040
Rattus norvegicus PHF19 RGD RGD:1310390