2. Gene
  3. GBP2 - guanylate binding protein 2 Gene

GBP2 - guanylate binding protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 2634 | Gene type: protein coding

About GBP2

Cytogenetic location: 1p22.2 Genomic coordinates (GRCh38): 1:89,106,132-89,126,114 (from NCBI)

This gene has 4 transcripts (splice variants), 144 orthologues and 10 paralogues. Ubiquitous expression in appendix (RPKM 36.9), urinary bladder (RPKM 31.7) and 24 other tissues.

Summary

This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013]

GBP2 Products(1)

mRNA Protein Name
NM_004120.5 NP_004111.2 guanylate-binding protein 2

GBP2 Protein Structure

GBP

GBP: Guanylate-binding protein, N-terminal domain (19 - 280)

GBP_C

GBP_C: Guanylate-binding protein, C-terminal domain (282 - 578)

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  • 591 a.a.
Protein Preferred Names Protein Names

guanylate-binding protein 2

GTP-binding protein 2

Recombinant GBP2 Proteins

Cat. No. Product Name Accession Purity
HY-P75787 GBP2 Protein, Human (HEK293, His) AAH73163.1 (M1-C588) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05308 GBP2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GBP2 RGD RGD:621810
Mus musculus GBP2 NCBI
Others GBP2 NCBI