2. Gene
  3. Esrra - estrogen related receptor, alpha Gene

Esrra - estrogen related receptor, alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Err1; Nr3b1; Estrra; ERRalpha

Gene ID: 26379 | Gene type: protein coding

About Esrra

Chromosome 19: 6,888,345-6,899,208 reverse strand.GRCm39:CM001012.3

This gene has 6 transcripts (splice variants), 175 orthologues, 8 paralogues and is associated with 45 phenotypes. Broad expression in duodenum adult (RPKM 141.5), small intestine adult (RPKM 86.) and 22 other tissues.

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human ESRRA (estrogen related receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Esrra Products(3)

mRNA Protein Name
NM_007953.3 NP_031979.2 steroid hormone receptor ERR1 isoform 1
NM_001413229.1 NP_001400158.1 steroid hormone receptor ERR1 isoform 2
NM_001413228.1 NP_001400157.1 steroid hormone receptor ERR1 isoform 2

Esrra Protein Structure

NR_DBD_ERR

NR_DBD_ERR: cd07170 (72 - 167)

NR_LBD_ERR

NR_LBD_ERR: cd06946 (195 - 418)

  • 0
  • 100
  • 200
  • 300
  • 422 a.a.
Protein Preferred Names Protein Names

steroid hormone receptor ERR1

ERR-alpha

Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1)

estrogen receptor related 1

estrogen receptor-like 1

nuclear receptor subfamily 3 group B member 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04537 ESRRA Human Pre-designed siRNA Set A / Unkown
HY-RS04538 Esrra Mouse Pre-designed siRNA Set A / Unkown
HY-RS04539 Esrra Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Esrra NCBI NCBI:2101