1. Gene
  2. Esrrg - estrogen-related receptor gamma Gene

Esrrg - estrogen-related receptor gamma Gene

Mus musculus

Also known as ERR3; Errg; NR3B3; mKIAA0832

Gene ID: 26381 | Gene type: protein coding

About Esrrg

Chromosome 1: 187,340,988-187,947,082 forward strand.GRCm39:CM000994.3

This gene has 5 transcripts (splice variants), 136 orthologues, 8 paralogues and is associated with 23 phenotypes. Biased expression in cerebellum adult (RPKM 6.9), kidney adult (RPKM 4.9) and 12 other tissues.

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Is expressed in several structures, including central nervous system; genitourinary system; gut; heart; and sensory organ. Orthologous to human ESRRG (estrogen related receptor gamma). [provided by Alliance of Genome Resources, Apr 2022]

Esrrg Products(5)

mRNA Protein Name
NM_011935.3 NP_036065.1 estrogen-related receptor gamma isoform1
NM_001357536.1 NP_001344465.1 estrogen-related receptor gamma isoform 3
NM_001357534.1 NP_001344463.1 estrogen-related receptor gamma isoform 2
NM_001243792.1 NP_001230721.1 estrogen-related receptor gamma isoform 2
NM_001357535.1 NP_001344464.1 estrogen-related receptor gamma isoform 2

Esrrg Protein Structure

NR_DBD_ERR

NR_DBD_ERR: cd07170 (121 - 217)

NR_LBD_ERR

NR_LBD_ERR: cd06946 (236 - 455)

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  • 458 a.a.
Protein Preferred Names Protein Names

estrogen-related receptor gamma

estrogen receptor-related protein 3

estrogen-related receptor 3

nuclear receptor subfamily 3 group B member 3

Orthologs Information

Species Symbol Source ID
Homo sapiens Esrrg NCBI NCBI:2104