PCOLCE2 - procollagen C-endopeptidase enhancer 2 Gene

Homo sapiens

Also known as PCPE2

Gene ID: 26577 | Gene type: protein coding

About PCOLCE2

Cytogenetic location: 3q23 Genomic coordinates (GRCh38): 3:142,817,874-142,889,083 (from NCBI)

This gene has 11 transcripts (splice variants), 214 orthologues and 35 paralogues. Biased expression in fat (RPKM 75.7), heart (RPKM 31.8) and 9 other tissues.

Summary

Enables collagen binding activity; heparin binding activity; and peptidase activator activity. Predicted to be involved in positive regulation of peptidase activity. Predicted to act upstream of or within cellular response to Leukemia Inhibitory Factor. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PCOLCE2 Products(1)

mRNA	Protein	Name
NM_013363.4	NP_037495.1	procollagen C-endopeptidase enhancer 2 precursor

PCOLCE2 Protein Structure

CUB

NTR

0
100
200
300
415 a.a.

Protein Preferred Names

Protein Names

procollagen C-endopeptidase enhancer 2

procollagen C-proteinase enhancer 2

Related Diseases

Diseases

Alias

Pulmonary Subvalvular Stenosis

Pulmonary Infundibular Stenosis	Congenital Infundibular Stenosis
Infundibular Pulmonic Stenosis	Infundibular Pulmonic Stenosis, Congenital
Subvalvular Pulmonic Stenosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10166	PCOLCE2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PCOLCE2	VGNC	VGNC:32643
Rattus norvegicus	PCOLCE2	RGD	RGD:1595195
Felis catus	PCOLCE2	VGNC	VGNC:68730
Macaca mulatta	PCOLCE2	VGNC	VGNC:75783
Mus musculus	PCOLCE2	MGD	MGI:1923727
Canis familiaris	PCOLCE2	VGNC	VGNC:44317

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