2. Gene
  3. GGT7 - gamma-glutamyltransferase 7 Gene

GGT7 - gamma-glutamyltransferase 7 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GGT4; GGTL3; GGTL5; D20S101

Gene ID: 2686 | Gene type: protein coding

About GGT7

Cytogenetic location: 20q11.22 Genomic coordinates (GRCh38): 20:34,844,720-34,872,856 (from NCBI)

This gene has 4 transcripts (splice variants), 244 orthologues and 6 paralogues. Ubiquitous expression in brain (RPKM 10.3), thyroid (RPKM 7.4) and 25 other tissues.

Summary

This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of Amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a LIGHT chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008]

GGT7 Products(2)

mRNA Protein Name
NM_001351702.2 NP_001338631.1 glutathione hydrolase 7 isoform 2
NM_178026.3 NP_821158.2 glutathione hydrolase 7 isoform 1

GGT7 Protein Structure

G_glu_transpept

G_glu_transpept: Gamma-glutamyltranspeptidase (155 - 653)

  • 0
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  • 600
  • 662 a.a.
Protein Preferred Names Protein Names

glutathione hydrolase 7

GGT 7

Related Diseases

Diseases Alias
Glutathionuria

Gamma-Glutamyltransferase Deficiency

Ggt Deficiency

Gtg Deficiency

Gamma-Glutamyltranspeptidase Deficiency

Glutathioninuria

Gamma-Glutamyl Transpeptidase Deficiency

Gamma-Glutamyl Transferase Deficiency

Ggt1 Deficiency

GLUTH
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05406 GGT7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GGT7 VGNC VGNC:41203
Macaca mulatta GGT7 VGNC VGNC:72921
Felis catus GGT7 VGNC VGNC:62541
Bos taurus GGT7 VGNC VGNC:29346
Mus musculus GGT7 MGD MGI:1913385
Rattus norvegicus GGT7 RGD RGD:619870