KCNV1 - potassium voltage-gated channel modifier subfamily V member 1 Gene

Homo sapiens

Also known as HNKA; KCNB3; KV2.3; KV8.1

Gene ID: 27012 | Gene type: protein coding

About KCNV1

Cytogenetic location: 8q23.2 Genomic coordinates (GRCh38): 8:109,963,636-109,975,771 (from NCBI)

This gene has 2 transcripts (splice variants), 193 orthologues and 31 paralogues. Restricted expression toward brain (RPKM 7.0).

Summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, Insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This protein is essentially present in the brain, and its role might be to inhibit the function of a particular class of outward rectifier Potassium Channel types. [provided by RefSeq, Jul 2008]

KCNV1 Products(1)

mRNA	Protein	Name
NM_014379.4	NP_055194.1	potassium voltage-gated channel subfamily V member 1

KCNV1 Protein Structure

BTB_2

Ion_trans

0
100
200
300
400
500 a.a.

Protein Preferred Names

Protein Names

potassium voltage-gated channel subfamily V member 1

neuronal potassium channel alpha subunit HNKA

Related Diseases

Diseases

Alias

Atrial Septal Defect 5

ASD5	Atrial Heart Septal Defect 5
Septal Defect, Atrial, Type 5

Familial Adult Myoclonic Epilepsy

Benign Adult Familial Myoclonus Epilepsy	Bafme
Benign Adult Familial Myoclonic Epilepsy	Fame
Familial Cortical Myoclonic Tremor And Epilepsy	Fcmte
Adcme	Autosomal Dominant Cortical Myoclonus And Epilepsy
Fam	Epilepsy, Myoclonic, Familial Adult
Epilepsy, Myoclonic, Benign Adult Familial, Type 2

Congenital Bile Acid Synthesis Defect

3-Beta-Hydroxy-Delta-5-C27-Steroid Oxidoreductase Deficiency	Cba
Cholestasis With Delta(4)-3-Oxosteroid-5-Beta-Reductase Deficiency	Basd
Bile Acid Synthesis Defect, Congenital, 1

Severe Congenital Neutropenia 3

Kostmann Syndrome	Infantile Agranulocytosis
Kostmann Disease	Scn3
Severe Congenital Neutropenia Type 3

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07183	KCNV1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	KCNV1	VGNC	VGNC:63050
Canis familiaris	KCNV1	VGNC	VGNC:42297
Bos taurus	KCNV1	VGNC	VGNC:30497
Macaca mulatta	KCNV1	VGNC	VGNC:73852
Mus musculus	KCNV1	MGD	MGI:1914748
Rattus norvegicus	KCNV1	RGD	RGD:621264

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