2. Gene
  3. DAPP1 - dual adaptor of phosphotyrosine and 3-phosphoinositides 1 Gene

DAPP1 - dual adaptor of phosphotyrosine and 3-phosphoinositides 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BAM32

Gene ID: 27071 | Gene type: protein coding

About DAPP1

Cytogenetic location: 4q23 Genomic coordinates (GRCh38): 4:99,816,827-99,872,333 (from NCBI)

This gene has 4 transcripts (splice variants), 201 orthologues and 9 paralogues. Broad expression in lymph node (RPKM 16.8), appendix (RPKM 14.4) and 15 other tissues.

Summary

Enables phosphatidylinositol-3,4,5-trisphosphate binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be involved in signal transduction. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

DAPP1 Products(2)

mRNA Protein Name
NM_001306151.2 NP_001293080.1 dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform 2
NM_014395.3 NP_055210.2 dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform 1

DAPP1 Protein Structure

SH2

SH2: SH2 domain (35 - 109)

PH

PH: PH domain (167 - 255)

  • 0
  • 100
  • 200
  • 280 a.a.
Protein Preferred Names Protein Names

dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

B-cell adapter molecule of 32 kDa

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03531 DAPP1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus DAPP1 RGD RGD:1310189
Mus musculus DAPP1 MGD MGI:1347063
Bos taurus DAPP1 VGNC VGNC:27880
Felis catus DAPP1 VGNC VGNC:61340
Canis familiaris DAPP1 VGNC VGNC:39773
Macaca mulatta DAPP1 VGNC VGNC:71630