NMRK2 - nicotinamide riboside kinase 2 Gene

Homo sapiens

Also known as MIBP; NRK2; ITGB1BP3

Gene ID: 27231 | Gene type: protein coding

About NMRK2

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:3,933,069-3,942,416 (from NCBI)

This gene has 5 transcripts (splice variants), 264 orthologues and 3 paralogues. Restricted expression toward heart (RPKM 167.4).

Summary

Enables ribosylnicotinamide kinase activity and ribosylnicotinate kinase activity. Predicted to be involved in NAD metabolic process. Predicted to act upstream of or within negative regulation of myoblast differentiation. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

NMRK2 Products(5)

mRNA	Protein	Name
NM_001289117.2	NP_001276046.1	nicotinamide riboside kinase 2 isoform 1
NM_001375467.2	NP_001362396.1	nicotinamide riboside kinase 2 isoform 3
NM_001375468.2	NP_001362397.1	nicotinamide riboside kinase 2 isoform 4
NM_001375469.2	NP_001362398.1	nicotinamide riboside kinase 2 isoform 5
NM_170678.3	NP_733778.1	nicotinamide riboside kinase 2 isoform 2

NMRK2 Protein Structure

AAA_18

0
100
200
230 a.a.

Protein Preferred Names

Protein Names

nicotinamide riboside kinase 2

NRK 2

Related Diseases

Diseases

Alias

Muscular Dystrophy, Congenital, Due To Integrin Alpha-7 Deficiency

Congenital Muscular Dystrophy Due To Integrin Alpha-7 Deficiency	Muscular Dystrophy, Congenital, Due To Itga7 Deficiency
Congenital Muscular Dystrophy With Integrin Alpha-7 Deficiency	Congenital Muscular Dystrophy With Itga7 Deficiency
Congenital Myopathy Due To Integrin Alpha-7 Deficiency	Myopathy, Congenital, Due To Integrin Alpha-7 Deficiency
Muscular Dystrophy Congenital Due To Integrin Alpha-7 Deficiency	MDCI
Dystrophy, Muscular, Congenital, Due To Integrin Alpha-7 Deficiency

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09387	NMRK2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	NMRK2	VGNC	VGNC:106842
Mus musculus	NMRK2	MGD	MGI:1916814
Rattus norvegicus	NMRK2	RGD	RGD:6486791
Macaca mulatta	NMRK2	VGNC	VGNC:75203

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