GNGT1 - G protein subunit gamma transducin 1 Gene

Homo sapiens

Also known as GNG1; HG3G1

Gene ID: 2792 | Gene type: protein coding

About GNGT1

Cytogenetic location: 7q21.3 Genomic coordinates (GRCh38): 7:93,906,567-93,911,265 (from NCBI)

This gene has 5 transcripts (splice variants), 143 orthologues and 11 paralogues. Restricted expression toward placenta (RPKM 1.6).

Summary

This gene encodes the gamma subunit of transducin, a guanine nucleotide-binding protein (G protein) that is found in rod outer segments. Transducin, also known as GMPase, mediates the activation of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase by rhodopsin. [provided by RefSeq, Jul 2016]

GNGT1 Products(2)

mRNA	Protein	Name
NM_001329426.2	NP_001316355.1	guanine nucleotide-binding protein G(T) subunit gamma-T1 precursor
NM_021955.5	NP_068774.1	guanine nucleotide-binding protein G(T) subunit gamma-T1 precursor

GNGT1 Protein Structure

G-gamma

0
74 a.a.

Protein Preferred Names

Protein Names

guanine nucleotide-binding protein G(T) subunit gamma-T1

guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1

Recombinant GNGT1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76369	GNGT1 Protein, Human (His)	P63211 (P2-C71)	≥95%

Related Diseases

Diseases

Alias

Night Blindness, Congenital Stationary, Autosomal Dominant 2

Congenital Stationary Night Blindness Autosomal Dominant 2	CSNBAD2
Hemeralopia	Night Blindness, Congenital Stationary, Rambusch Type
Rambusch Type Congenital Stationary Night Blindness	Congenital Stationary Night Blindness Rambusch Type
Hemeralopia Congenital Essential	Blindness, Night, Stationary, Congenital, Autosomal Dominant, Type 2

Leber Plus Disease

Leber Congenital Amaurosis	Lca
Leber'S Amaurosis	Leber'S Disease
Amaurosis Congenita Of Leber	Amaurosis Congenita Of Leber, Type 1
Lhon Plus Disease	Congenital Absence Of The Rods And Cones
Congenital Retinal Blindness	Crb
Congenital Amaurosis Of Retinal Origin	Leber'S Congenital Amaurosis
Leber Congenital Amaurosis 1	Leber'S Congenital Tapetoretinal Degeneration
Leber'S Congenital Tapetoretinal Dysplasia	Lca1
Leber Congenital Amaurosis Type 1	Retinal Blindness, Congenital
Amaurosis, Leber Congenital	Dysgenesis Neuroepithelialis Retinae
Hereditary Epithelial Dysplasia Of Retina	Hereditary Retinal Aplasia
Heredoretinopathia Congenitalis	Leber Abiotrophy
Leber Congenital Tapetoretinal Degeneration	Lebers Congenital Amaurosis
Optic Atrophy, Hereditary, Leber

Fundus Dystrophy

Retinal Dystrophy	Retinal Dystrophies
Dystrophy, Retinal

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05562	GNGT1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	GNGT1	VGNC	VGNC:73098
Mus musculus	GNGT1	MGD	MGI:109165
Felis catus	GNGT1	VGNC	VGNC:62624
Bos taurus	GNGT1	VGNC	VGNC:29470
Rattus norvegicus	GNGT1	RGD	RGD:1595475
Canis familiaris	GNGT1	VGNC	VGNC:41324
Others	GNGT1	NCBI

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