2. Gene
  3. CXCL17 - C-X-C motif chemokine ligand 17 Gene

CXCL17 - C-X-C motif chemokine ligand 17 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DMC; VCC1; Dcip1; VCC-1; UNQ473

Gene ID: 284340 | Gene type: protein coding

About CXCL17

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:42,428,278-42,442,946 (from NCBI)

This gene has 2 transcripts (splice variants) and 84 orthologues. Biased expression in stomach (RPKM 182.1), lung (RPKM 72.2) and 3 other tissues.

Summary

The protein encoded by this gene is a mucosal chemokine that attracts immature dendritic cells and blood monocytes to the lungs. The encoded protein also promotes tumorigenesis through an angiogenic activity. Finally, this protein exhibits strong antimicrobial activity against E. coli, S. aureus, Salmonella, P. aeruginosa, and C. albicans. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]

CXCL17 Products(1)

mRNA Protein Name
NM_198477.3 NP_940879.1 C-X-C motif chemokine 17 precursor

CXCL17 Protein Structure

CXCL17

CXCL17: VEGF co-regulated chemokine 1 (23 - 111)

  • 0
  • 100
  • 119 a.a.
Protein Preferred Names Protein Names

C-X-C motif chemokine 17

6-Cys CXCL17

Recombinant CXCL17 Proteins

Cat. No. Product Name Accession Purity
HY-P71878 CXCL17 Protein, Human Q6UXB2 (S22-119L) ≥95%

Related Diseases

Diseases Alias
Cholera

Vibrio Cholerae Infection

Cholera - Vibrio Cholerae

Cholera Due To Vibrio Cholerae

Vibrio Cholerae

Cholera Syndrome

Asiatic Cholera

Epidemic Cholera
Photokeratitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03390 CXCL17 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CXCL17 VGNC VGNC:109613
Rattus norvegicus CXCL17 RGD RGD:1304717
Canis familiaris CXCL17 VGNC VGNC:49733
Mus musculus CXCL17 MGD MGI:2387642
Bos taurus CXCL17 VGNC VGNC:27852
Others CXCL17 NCBI