2. Gene
  3. NKIRAS2 - NFKB inhibitor interacting Ras like 2 Gene

NKIRAS2 - NFKB inhibitor interacting Ras like 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as KBRAS2; kappaB-Ras2

Gene ID: 28511 | Gene type: protein coding

About NKIRAS2

Cytogenetic location: 17q21.2 Genomic coordinates (GRCh38): 17:42,017,576-42,025,641 (from NCBI)

This gene has 14 transcripts (splice variants), 204 orthologues and 35 paralogues. Ubiquitous expression in placenta (RPKM 30.4), esophagus (RPKM 22.7) and 25 other tissues.

Summary

Predicted to enable GTPase activating protein binding activity. Predicted to be involved in I-kappaB kinase/NF-kappaB signaling. Predicted to act upstream of or within several processes, including Ral protein signal transduction; regulation of signal transduction; and surfactant homeostasis. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NKIRAS2 Products(5)

mRNA Protein Name
NM_001001349.2 NP_001001349.1 NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform a
NM_001144927.2 NP_001138399.1 NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform a
NM_001144928.2 NP_001138400.1 NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform b
NM_001144929.2 NP_001138401.1 NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform c
NM_017595.6 NP_060065.2 NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform a

NKIRAS2 Protein Structure

Ras

Ras: Ras family (6 - 169)

  • 0
  • 100
  • 191 a.a.
Protein Preferred Names Protein Names

NF-kappa-B inhibitor-interacting Ras-like protein 2

I-kappa-B-interacting Ras-like protein 2

Related Diseases

Diseases Alias
Diffuse Lipomatosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09321 NKIRAS2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NKIRAS2 VGNC VGNC:75205
Mus musculus NKIRAS2 MGD MGI:1919216
Rattus norvegicus NKIRAS2 RGD RGD:1307363
Bos taurus NKIRAS2 VGNC VGNC:32095
Canis familiaris NKIRAS2 VGNC VGNC:43830