RUFY4 - RUN and FYVE domain containing 4 Gene

Homo sapiens

Also known as ZFYVE31

Gene ID: 285180 | Gene type: protein coding

About RUFY4

This gene has 11 transcripts (splice variants), 109 orthologues and 1 paralogue. Broad expression in spleen (RPKM 1.0), lymph node (RPKM 0.6) and 16 other tissues.

Summary

Enables phosphatidylinositol-3-phosphate binding activity. Involved in autophagosome assembly; cellular response to interleukin-4; and positive regulation of macroautophagy. Located in autophagosome. [provided by Alliance of Genome Resources, Apr 2022]

RUFY4 Products(1)

mRNA	Protein	Name
NM_198483.4	NP_940885.2	RUN and FYVE domain-containing protein 4

RUFY4 Protein Structure

RUN

0
100
200
300
400
500
571 a.a.

Protein Preferred Names

Protein Names

RUN and FYVE domain-containing protein 4

Related Diseases

Diseases

Alias

Melnick-Needles Syndrome

MNS	Melnick-Needles Osteodysplasty
Osteodysplasty Of Melnick And Needles	Osteochondrodysplasias

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12346	RUFY4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	RUFY4	RGD	RGD:1560678
Mus musculus	RUFY4	MGD	MGI:3588214
Canis familiaris	RUFY4	VGNC	VGNC:57393
Macaca mulatta	RUFY4	VGNC	VGNC:99400
Bos taurus	RUFY4	VGNC	VGNC:34216
Felis catus	RUFY4	VGNC	VGNC:64821

Name
Email *

	Sorry, but the email address you supplied was invalid.