2. Gene
  3. CCDC66 - coiled-coil domain containing 66 Gene

CCDC66 - coiled-coil domain containing 66 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 285331 | Gene type: protein coding

About CCDC66

Cytogenetic location: 3p14.3 Genomic coordinates (GRCh38): 3:56,557,156-56,621,837 (from NCBI)

This gene has 22 transcripts (splice variants) and 176 orthologues. Ubiquitous expression in testis (RPKM 7.3), endometrium (RPKM 5.1) and 25 other tissues.

Summary

Enables microtubule binding activity. Involved in cilium assembly; microtubule bundle formation; and regulation of protein localization to cilium. Located in several cellular components, including Flemming body; microtubule cytoskeleton; and photoreceptor inner segment. [provided by Alliance of Genome Resources, Apr 2022]

CCDC66 Products(14)

mRNA Protein Name
NM_001012506.5 NP_001012524.4 coiled-coil domain-containing protein 66 isoform 2
NM_001141947.3 NP_001135419.1 coiled-coil domain-containing protein 66 isoform 1
NM_001353147.1 NP_001340076.1 coiled-coil domain-containing protein 66 isoform 3
NM_001353148.1 NP_001340077.1 coiled-coil domain-containing protein 66 isoform 4
NM_001353149.1 NP_001340078.1 coiled-coil domain-containing protein 66 isoform 5
NM_001353150.1 NP_001340079.1 coiled-coil domain-containing protein 66 isoform 6
NM_001353151.1 NP_001340080.1 coiled-coil domain-containing protein 66 isoform 7
NM_001353152.1 NP_001340081.1 coiled-coil domain-containing protein 66 isoform 2
NM_001353153.1 NP_001340082.1 coiled-coil domain-containing protein 66 isoform 2
NM_001353154.1 NP_001340083.1 coiled-coil domain-containing protein 66 isoform 8
NM_001353155.1 NP_001340084.1 coiled-coil domain-containing protein 66 isoform 9
NM_001353156.1 NP_001340085.1 coiled-coil domain-containing protein 66 isoform 10
NM_001353158.1 NP_001340087.1 coiled-coil domain-containing protein 66 isoform 11
NM_001353160.1 NP_001340089.1 coiled-coil domain-containing protein 66 isoform 12

CCDC66 Protein Structure

CCDC66

CCDC66: Coiled-coil domain-containing protein 66 (409 - 564)

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  • 948 a.a.
Protein Preferred Names Protein Names

coiled-coil domain-containing protein 66

Related Diseases

Diseases Alias
Cone-Rod Dystrophy 1

CORD1

Crd1

Cone-Rod Retinal Dystrophy-1

Retinitis Pigmentosa 1
Retinal Degeneration

Degeneration Of Retina
Hirschsprung Disease 1

Hirschsprung Disease

Aganglionic Megacolon

Hscr

Hirschsprung'S Disease

Congenital Megacolon

Congenital Intestinal Aganglionosis

Colonic Aganglionosis

Hirschsprung Disease, Susceptibility To, 1

Hirschsprung Disease, Protection Against

HSCR1

Mgc

Pelvirectal Achalasia

Total Intestinal Aganglionosis

Megacolon, Aganglionic

Macrocolon

Hscr 1

Hirschsprung Disease Type 1

Hirschsprung Disease, Type 1

Congenital Dilatation Of Colon

Aganglionosis

Congenital Aganglionic Megacolon

Aganglionosis Of Colon

Bowel Aganglionosis

Colon Aganglionosis

Hirschsprung Megacolon
Fundus Dystrophy

Retinal Dystrophy

Retinal Dystrophies

Dystrophy, Retinal
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02052 CCDC66 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CCDC66 MGD MGI:2443639
Canis familiaris CCDC66 VGNC VGNC:38850
Macaca mulatta CCDC66 VGNC VGNC:70883
Rattus norvegicus CCDC66 RGD RGD:1560873
Bos taurus CCDC66 VGNC VGNC:26909
Felis catus CCDC66 VGNC VGNC:60511