2. Gene
  3. GPR37 - G protein-coupled receptor 37 Gene

GPR37 - G protein-coupled receptor 37 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PAELR; EDNRBL; hET(B)R-LP

Gene ID: 2861 | Gene type: protein coding

About GPR37

Cytogenetic location: 7q31.33 Genomic coordinates (GRCh38): 7:124,743,885-124,765,792 (from NCBI)

This gene has 1 transcript (splice variant), 268 orthologues and 15 paralogues. Biased expression in brain (RPKM 26.2), testis (RPKM 10.2) and 4 other tissues.

Summary

This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease. [provided by RefSeq, Oct 2012]

GPR37 Products(1)

mRNA Protein Name
NM_005302.5 NP_005293.1 prosaposin receptor GPR37 precursor

GPR37 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (278 - 548)

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  • 613 a.a.
Protein Preferred Names Protein Names

prosaposin receptor GPR37

ETBR-LP-1

Recombinant GPR37 Proteins

Cat. No. Product Name Accession Purity
HY-P76376 GPR37 Protein, Human (HEK293, His) O15354 (M1-M265) ≥95%

Related Diseases

Diseases Alias
Juvenile-Onset Parkinson'S Disease

Juvenile-Onset Parkinson Disease
Epilepsy, Familial Temporal Lobe, 6

ETL6

Familial Temporal Lobe Epilepsy 6
Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05709 GPR37 Human Pre-designed siRNA Set A / Unkown
HY-RS05710 GPR37L1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus GPR37 VGNC VGNC:80054
Mus musculus GPR37 MGD MGI:1313297
Macaca mulatta GPR37 VGNC VGNC:73135
Rattus norvegicus GPR37 RGD RGD:619848
Bos taurus GPR37 VGNC VGNC:29585
Canis familiaris GPR37 VGNC VGNC:41432
Others GPR37 NCBI