2. Gene
  3. LIN9 - lin-9 DREAM MuvB core complex component Gene

LIN9 - lin-9 DREAM MuvB core complex component Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TGS; BARA; TGS1; TGS2; Lin-9; BARPsv

Gene ID: 286826 | Gene type: protein coding

About LIN9

Cytogenetic location: 1q42.12 Genomic coordinates (GRCh38): 1:226,231,149-226,309,767 (from NCBI)

This gene has 6 transcripts (splice variants) and 220 orthologues. Broad expression in testis (RPKM 3.7), heart (RPKM 2.8) and 24 other tissues.

Summary

This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

LIN9 Products(9)

mRNA Protein Name
NM_001270409.1 NP_001257338.1 protein lin-9 homolog isoform 2
NM_001270410.2 NP_001257339.1 protein lin-9 homolog isoform 3
NM_001366237.1 NP_001353166.1 protein lin-9 homolog isoform 4
NM_001366238.1 NP_001353167.1 protein lin-9 homolog isoform 5
NM_001366239.1 NP_001353168.1 protein lin-9 homolog isoform 6
NM_001366240.1 NP_001353169.1 protein lin-9 homolog isoform 7
NM_001366241.1 NP_001353170.1 protein lin-9 homolog isoform 3
NM_001366245.2 NP_001353174.1 protein lin-9 homolog isoform 8
NM_173083.3 NP_775106.2 protein lin-9 homolog isoform 1

LIN9 Protein Structure

DIRP

DIRP: DIRP (143 - 247)

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  • 500
  • 558 a.a.
Protein Preferred Names Protein Names

protein lin-9 homolog

TUDOR gene similar protein

Related Diseases

Diseases Alias
Distal Muscular Dystrophy With Anterior Tibial Onset

Dmat
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07679 LIN9 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus LIN9 VGNC VGNC:30898
Canis familiaris LIN9 VGNC VGNC:42687
Macaca mulatta LIN9 VGNC VGNC:74166
Mus musculus LIN9 MGD MGI:1919818
Rattus norvegicus LIN9 RGD RGD:1591104
Felis catus LIN9 VGNC VGNC:63235