2. Gene
  3. KLF15 - KLF transcription factor 15 Gene

KLF15 - KLF transcription factor 15 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as KKLF

Gene ID: 28999 | Gene type: protein coding

About KLF15

Cytogenetic location: 3q21.3 Genomic coordinates (GRCh38): 3:126,288,125-126,357,408 (from NCBI)

This gene has 2 transcripts (splice variants), 251 orthologues and 22 paralogues. Broad expression in fat (RPKM 10.7), ovary (RPKM 8.2) and 17 other tissues.

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of peptidyl-lysine acetylation and positive regulation of transcription by RNA polymerase II. Located in nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

KLF15 Products(1)

mRNA Protein Name
NM_014079.4 NP_054798.1 Krueppel-like factor 15

KLF15 Protein Structure

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (337 - 359)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (368 - 391)

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  • 416 a.a.
Protein Preferred Names Protein Names

Krueppel-like factor 15

Kruppel like factor 15

Related Diseases

Diseases Alias
Aortic Aneurysm

Aortic Rupture

Thoracoabdominal Aortic Aneurysm, Ruptured

Ruptured Aortic Aneurysm

Aortic Aneurysms

Aortic Aneurysm Without Mention Of Rupture Nos

Ruptured Abdominal Aortic Aneurysm

Aortic Aneurysm, Ruptured

Ruptured Thoracic Aortic Aneurysm
Glomerular Disease
Muscular Atrophy

Muscle Wasting

Amyotrophia

Wasting - Muscle

Skeletal Muscle Atrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07336 KLF15 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris KLF15 VGNC VGNC:42434
Rattus norvegicus KLF15 RGD RGD:70918
Bos taurus KLF15 VGNC VGNC:30629
Felis catus KLF15 VGNC VGNC:63132
Mus musculus KLF15 MGD MGI:1929988
Macaca mulatta KLF15 VGNC VGNC:73829