2. Gene
  3. Sigmar1 - sigma non-opioid intracellular receptor 1 Gene

Sigmar1 - sigma non-opioid intracellular receptor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Oprs1

Gene ID: 29336 | Gene type: protein coding

About Sigmar1

Primary_assembly 5: 56,904,159-56,907,017 reverse strand.mRatBN7.2:CM026978.1

This gene has 2 transcripts (splice variants), 206 orthologues and is associated with 14 phenotypes. Biased expression in Liver (RPKM 836.2), Kidney (RPKM 18.1) and 9 other tissues.

Summary

Enables G protein-coupled Opioid Receptor activity. Involved in nervous system development. Predicted to be located in membrane; nuclear envelope; and postsynaptic density. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 16 and distal spinal muscular atrophy 2. Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Sigmar1 Products(1)

mRNA Protein Name
NM_030996.2 NP_112258.2 sigma non-opioid intracellular receptor 1

Sigmar1 Protein Structure

ERG2_Sigma1R

ERG2_Sigma1R: pfam04622 (25 - 213)

  • 0
  • 100
  • 200
  • 223 a.a.
Protein Preferred Names Protein Names

sigma non-opioid intracellular receptor 1

opioid receptor, sigma 1

sigma 1-type opioid receptor

sigma1-receptor

sigma1R

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12908 SIGMAR1 Human Pre-designed siRNA Set A / Unkown
HY-RS12909 Sigmar1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS12910 Sigmar1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sigmar1 NCBI NCBI:10280