2. Gene
  3. P2rx4 - purinergic receptor P2X 4 Gene

P2rx4 - purinergic receptor P2X 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 29659 | Gene type: protein coding

About P2rx4

Primary_assembly 12: 33,844,396-33,862,253 reverse strand.mRatBN7.2:CM026985.1

This gene has 4 transcripts (splice variants), 211 orthologues, 6 paralogues and is associated with 5 phenotypes. Biased expression in Spleen (RPKM 179.), Kidney (RPKM 171.7) and 9 other tissues.

Summary

Enables several functions, including ATP binding activity; ligand-gated cation channel activity; and transition metal ion binding activity. Involved in several processes, including cellular response to zinc ion; neuronal action potential; and positive regulation of microglial cell migration. Located in several cellular components, including dendritic spine; neuronal cell body; and postsynaptic density. Is integral component of plasma membrane. Biomarker of congestive heart failure. Orthologous to human P2RX4 (purinergic receptor P2X 4). [provided by Alliance of Genome Resources, Apr 2022]

P2rx4 Products(1)

mRNA Protein Name
NM_031594.2 NP_113782.2 P2X purinoceptor 4

P2rx4 Protein Structure

P2X_receptor

P2X_receptor: pfam00864 (12 - 360)

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  • 388 a.a.
Protein Preferred Names Protein Names

P2X purinoceptor 4

ATP receptor

P2X4

purinergic receptor P2X, ligand-gated ion channel 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09906 P2RX4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09907 P2rx4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09908 P2rx4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2rx4 NCBI NCBI:5025