2. Gene
  3. SNX8 - sorting nexin 8 Gene

SNX8 - sorting nexin 8 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as Mvp1

Gene ID: 29886 | Gene type: protein coding

About SNX8

Cytogenetic location: 7p22.3 Genomic coordinates (GRCh38): 7:2,251,770-2,354,497 (from NCBI)

This gene has 9 transcripts (splice variants), 220 orthologues and 15 paralogues. Broad expression in spleen (RPKM 12.6), testis (RPKM 7.0) and 24 other tissues.

Summary

Enables identical protein binding activity and phosphatidylinositol binding activity. Involved in early endosome to Golgi transport and intracellular protein transport. Located in early endosome membrane. Colocalizes with retromer complex. [provided by Alliance of Genome Resources, Apr 2022]

SNX8 Products(1)

mRNA Protein Name
NM_013321.4 NP_037453.1 sorting nexin-8

SNX8 Protein Structure

PX

PX: PX domain (84 - 178)

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  • 465 a.a.
Protein Preferred Names Protein Names

sorting nexin-8

Related Diseases

Diseases Alias
Atrial Tachyarrhythmia With Short Pr Interval

Lown-Ganong-Levine Syndrome

Syndrome Of Short P-R Interval, Normal Qrs Complexes, And Supraventricular Tachycardias

Lgl Syndrome
Tetralogy Of Fallot

TOF

Fallot Tetralogy

Ventricular Septal Defect With Pulmonary Stenosis Or Atresia, Dextraposition Of Aorta, And Hypertrophy Of Right Ventricle

Tetrad Of Fallot

Fallot Tetrad

Fallot Disease

Fallot Complex

Subpulmonic Stenosis, Ventricular Septal Defect, Overriding Aorta, And Right Ventricular Hypertrophy

Interventricular Septal Defect With Dextroposition Of Aorta, Pulmonary Stenosis And Hypertrophy Of Right Ventricle

Interventricular Septal Defect, In Tetralogy Of Fallot

Ventricular Septal Defect With Obstructed Right Ventricular Outflow

Tof - [Tetralogy Of Fallot]

Pulmonary Atresia With Ventricular Septal Defect [Fallot Type]

Pulmonary Atresia, Ventricular Septal Defect And Mapcas

Pulmonary Atresia With Ventricular Septal Defect And Systemic-To-Pulmonary Collateral Arteries [Fallot Type]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13547 SNX8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SNX8 VGNC VGNC:65559
Canis familiaris SNX8 VGNC VGNC:46644
Bos taurus SNX8 VGNC VGNC:35114
Macaca mulatta SNX8 VGNC VGNC:77703
Rattus norvegicus SNX8 RGD RGD:1305791
Mus musculus SNX8 MGD MGI:2443816