Brdt - bromodomain testis associated Gene

Rattus norvegicus

Gene ID: 305123 | Gene type: protein coding

About Brdt

Restricted expression toward (RPKM 382.8).

Summary

Predicted to enable lysine-acetylated histone binding activity and nucleosomal histone binding activity. Involved in chromatin remodeling and spermatogenesis. Located in nucleus. Human ortholog(s) of this gene implicated in azoospermia; oligospermia; and spermatogenic failure 21. Orthologous to human BRDT (bromodomain testis associated). [provided by Alliance of Genome Resources, Apr 2022]

Brdt Products(2)

mRNA	Protein	Name
NM_001012031.3	NP_001012031.1	bromodomain testis-specific protein isoform 2
NM_001402393.1	NP_001389322.1	bromodomain testis-specific protein isoform 1

Brdt Protein Structure

Bromo_Brdt_I_like

Bromodomain

0
100
200
300
326 a.a.

Protein Preferred Names

Protein Names

bromodomain testis-specific protein

bromodomain, testis-specific

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-112090	ABBV-744	Inhibitor	99.97%	Phase 1

Pre-clinical Phase

Bioactive Molecules (16)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-136570	GSK778	Inhibitor	98.93%	Unkown
HY-136571	GSK046	Inhibitor	99.65%	Unkown
HY-130622	LT052	Inhibitor	98.77%	Unkown
HY-112610	CF53	Inhibitor	99.78%	Unkown
HY-114504	RVX-297	Inhibitor	96.59%	Unkown
HY-131061	BET bromodomain inhibitor 1	Inhibitor	99.91%	Unkown
HY-138563	GSK973	Inhibitor	99.46%	Unkown
HY-160558	PLK1/BRD4-IN-3	Inhibitor	/	Unkown
HY-126325	BY27	Inhibitor	/	Unkown
HY-155680	BET BD2-IN-1	Inhibitor	/	Unkown
HY-152213	BET-IN-13	Inhibitor	/	Unkown
HY-150684	GXH-II-052	Inhibitor	/	Unkown
HY-150683	NC-III-49-1	Inhibitor	/	Unkown
HY-149806	Bromodomain IN-2	Inhibitor	/	Unkown
HY-136794	SB-284851-BT	Inhibitor	/	Unkown
HY-136570A	GSK778 hydrochloride	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Brdt	NCBI	NCBI:676

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