SLC29A2 - solute carrier family 29 member 2 Gene

Homo sapiens

Also known as ENT2; DER12; HNP36

Gene ID: 3177 | Gene type: protein coding

About SLC29A2

Cytogenetic location: 11q13.2 Genomic coordinates (GRCh38): 11:66,362,521-66,372,446 (from NCBI)

This gene has 7 transcripts (splice variants), 266 orthologues and 3 paralogues. Ubiquitous expression in duodenum (RPKM 6.4), small intestine (RPKM 4.5) and 23 other tissues.

Summary

The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008]

SLC29A2 Products(3)

mRNA	Protein	Name
NM_001300868.2	NP_001287797.1	equilibrative nucleoside transporter 2 isoform a
NM_001300869.2	NP_001287798.1	equilibrative nucleoside transporter 2 isoform b
NM_001532.3	NP_001523.2	equilibrative nucleoside transporter 2 isoform a

SLC29A2 Protein Structure

Nucleoside_tran

0
100
200
300
400
456 a.a.

Protein Preferred Names

Protein Names

equilibrative nucleoside transporter 2

36 kDa nucleolar protein HNP36

Related Diseases

Diseases

Alias

Hepatic Adenomas, Familial

Hepatic Adenoma, Somatic	Familial Hepatic Adenoma
Familial Liver Cell Adenomas	Liver Cell Adenomas, Familial
Hepatic Adenomas Familial	HEPAF
Ha	Hepatocellular Adenomas
Hepatocellular Adenoma

Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia	B-Cell Chronic Lymphocytic Leukemia
CLL	B-Cell Chronic Lymphoid Leukemia
Chronic Lymphatic Leukemia	Chronic Lymphocytic Leukaemia
Lymphoplasmacytic Leukemia	Small Lymphocytic Lymphoma
Leukemia, Chronic Lymphatic	B-Cell Chronic Lymphocytic Leukaemia
Chronic Lymphatic Leukaemia	Lymphoplasmacytic Leukaemia
B Cell Chronic Lymphocytic Leukemia	Chronic B-Cell Lymphocytic Leukemia
Leukemia, Lymphocytic, Chronic	B-Cll
Chronic Lymphoid Leukemia	Leukemia Lymphocytic Chronic
Lymphoma Small Lymphocytic	Leukemia, Lymphocytic, Chronic, B-Cell

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13154	SLC29A2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SLC29A2	VGNC	VGNC:65296
Macaca mulatta	SLC29A2	VGNC	VGNC:77446
Rattus norvegicus	SLC29A2	RGD	RGD:69296
Bos taurus	SLC29A2	VGNC	VGNC:34794
Canis familiaris	SLC29A2	VGNC	VGNC:46334
Mus musculus	SLC29A2	MGD	MGI:1345278
Others	SLC29A2	NCBI

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