2. Gene
  3. ARL16 - ADP ribosylation factor like GTPase 16 Gene

ARL16 - ADP ribosylation factor like GTPase 16 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 339231 | Gene type: protein coding

About ARL16

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:81,681,165-81,683,797 (from NCBI)

This gene has 13 transcripts (splice variants), 147 orthologues and 30 paralogues. Ubiquitous expression in kidney (RPKM 11.1), thyroid (RPKM 10.4) and 25 other tissues.

Summary

The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). This protein has been shown to have an inhibitory role in the cellular Antiviral response. This gene product interacts with the C-terminal domain of the DEXD/H-box helicase 58 (DDX58) gene product. This interaction was found to suppress the association between the DDX58 gene product and RNA, thereby negatively regulating the activity of the DDX58 gene product. [provided by RefSeq, Jul 2016]

ARL16 Products(3)

mRNA Protein Name
NM_001040025.3 NP_001035114.2 ADP-ribosylation factor-like protein 16 isoform 1
NM_001329608.2 NP_001316537.1 ADP-ribosylation factor-like protein 16 isoform 2
NM_001329609.2 NP_001316538.1 ADP-ribosylation factor-like protein 16 isoform 3

ARL16 Protein Structure

Arf

Arf: ADP-ribosylation factor family (21 - 191)

  • 0
  • 100
  • 197 a.a.
Protein Preferred Names Protein Names

ADP-ribosylation factor-like protein 16

Related Diseases

Diseases Alias
Childhood-Onset Schizophrenia

Childhood Schizophrenia

Schizophrenia, Childhood
Accommodative Esotropia

Esotropia With Accommodative Compensation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00984 ARL16 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ARL16 VGNC VGNC:99118
Bos taurus ARL16 VGNC VGNC:26141
Mus musculus ARL16 MGD MGI:1917567
Rattus norvegicus ARL16 RGD RGD:1590059
Felis catus ARL16 VGNC VGNC:59924
Canis familiaris ARL16 VGNC VGNC:38109