CCDC39 - coiled-coil domain containing 39 Gene

Homo sapiens

Also known as FAP59; CFAP59; CILD14

Gene ID: 339829 | Gene type: protein coding

About CCDC39

Cytogenetic location: 3q26.33 Genomic coordinates (GRCh38): 3:180,614,008-180,679,489 (from NCBI)

This gene has 11 transcripts (splice variants), 204 orthologues and is associated with 3 phenotypes. Broad expression in testis (RPKM 5.3), lymph node (RPKM 2.5) and 23 other tissues.

Summary

The protein encoded by this gene is involved in the motility of cilia and flagella. The encoded protein is essential for the assembly of dynein regulatory and inner dynein arm complexes, which regulate ciliary beat. Defects in this gene are a cause of primary ciliary dyskinesia type 14 (CILD14). [provided by RefSeq, Jul 2011]

CCDC39 Products(1)

mRNA	Protein	Name
NM_181426.2	NP_852091.1	coiled-coil domain-containing protein 39

Protein Preferred Names

Protein Names

coiled-coil domain-containing protein 39

Related Diseases

Diseases

Alias

Ciliary Dyskinesia, Primary, 14

Primary Ciliary Dyskinesia 14	CILD14
Primary Ciliary Dyskinesia 14 With Or Without Situs Inversus	Ciliary Dyskinesia, Primary, 14, With Or Without Situs Inversus
Ics14	Immotile Cilia Syndrome 14
Dyskinesia, Ciliary, Primary, Type 14

Primary Ciliary Dyskinesia

Immotile Cilia Syndrome	Kartagener Syndrome
Dextrocardia Bronchiectasis And Sinusitis	Pcd
Ciliary Motility Disorders	Ciliary Motility Disorder
Immotile Ciliary Syndrome	Ciliary Dyskinesia Primary
Ics	Polynesian Bronchiectasis
Dextrocardia-Bronchiectasis-Sinusitis Syndrome	Immotile Cilia Syndrome, Kartagener Type
Primary Ciliary Dyskinesia And Situs Inversus	Primary Ciliary Dyskinesia, Kartagener Type
Siewert Syndrome	Dyskinesia, Ciliary, Primary

Infertility

Situs Inversus

Situs Inversus Viscerum	Laterality Sequence
Complete Transposition	Siv

Kartagener Syndrome

Kartagener'S Syndrome

Visceral Heterotaxy

Situs Ambiguus	Heterotaxia
Heterotaxy Syndrome	Heterotaxy
Lateralization Defect	Situs Ambiguous
Left Isomerism	Htx
Ivemark Syndrome	Right Isomerism
Situs Ambiguus Viscerum	Incomplete Situs Inversus
Partial Situs Inversus	Heterotaxy, Visceral
Asplenia Syndrome	Bilateral Left-Sidedness
Polysplenia Syndrome	Moller Syndrome

Acantholytic Acanthoma

Verrucous Papilloma

Skin Papilloma

Cutaneous Papilloma	Papilloma Of Skin
Papilloma Skin

Bronchiectasis

Polynesian Bronchiectasis	Kartagener Syndrome
Bronchiectasis Nos

Nasal Cavity Lymphoma

Lymphoma Of Nasal Cavity

Lymphoma Of The Nasal Cavity

Joubert Syndrome 25

JBTS25

Joubert Syndrome, Type 25

Ciliary Dyskinesia, Primary, 30

Primary Ciliary Dyskinesia 30	CILD30
Ciliary Dyskinesia, Primary, 30, With Or Without Situs Inversus	Primary Ciliary Dyskinesia 30 Without Situs Inversus
Primary Ciliary Dyskinesia 30 With Or Without Situs Inversus	Dyskinesia, Ciliary, Primary, Type 30

Epidermodysplasia Verruciformis 1

Epidermodysplasia Verruciformis	Epidermodysplasia Verruciformis, Susceptibility To, 1
Lutz-Lewandowsky Epidermodysplasia Verruciformis	EV1
Lewandowsky-Lutz Syndrome	Ev

Dextrocardia

Heart Predominantly In Right Hemithorax	Heart In Right Chest
Right-Sided Heart	Congenital Dextrocardia Of Heart
Transposition Of Heart

Common Wart

Verruca Vulgaris	Viral Warts Nos
Filiform Warts	Digitate Warts

Paranasal Sinus Disease

Paranasal Sinus Diseases

Disorder Of Nasal Sinus

Acute Endometritis

Ciliary Dyskinesia, Primary, 4

Primary Ciliary Dyskinesia 4	CILD4
Ciliary Dyskinesia, Primary, 4, With Or Without Situs Inversus	Primary Ciliary Dyskinesia 4 With Or Without Situs Inversus
Primary Ciliary Dyskinesia, 4

Ciliary Dyskinesia, Primary, 8

Primary Ciliary Dyskinesia 8	CILD8
Ciliary Dyskinesia, Primary, 8, With Or Without Situs Inversus	Primary Ciliary Dyskinesia 8 With Or Without Situs Inversus

Middle Ear Disease

Middle Ear Anomaly

Disorder Of Middle Ear

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02045	CCDC39 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CCDC39	VGNC	VGNC:50106
Macaca mulatta	CCDC39	VGNC	VGNC:110376
Rattus norvegicus	CCDC39	RGD	RGD:1306277
Felis catus	CCDC39	VGNC	VGNC:102621
Canis familiaris	CCDC39	VGNC	VGNC:49810
Mus musculus	CCDC39	MGD	MGI:1289263

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