2. Gene
  3. MSGN1 - mesogenin 1 Gene

MSGN1 - mesogenin 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MSOG; pMsgn1

Gene ID: 343930 | Gene type: protein coding

About MSGN1

Cytogenetic location: 2p24.2 Genomic coordinates (GRCh38): 2:17,816,460-17,817,798 (from NCBI)

This gene has 1 transcript (splice variant), 176 orthologues and 2 paralogues.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in mesoderm formation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within segment specification and somitogenesis. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

MSGN1 Products(1)

mRNA Protein Name
NM_001105569.3 NP_001099039.1 mesogenin-1

MSGN1 Protein Structure

HLH

HLH: Helix-loop-helix DNA-binding domain (125 - 178)

  • 0
  • 100
  • 193 a.a.
Protein Preferred Names Protein Names

mesogenin-1

pMesogenin1

Related Diseases

Diseases Alias
Spondylocostal Dysostosis 4, Autosomal Recessive

SCDO4

Spondylocostal Dysostosis 4

Autosomal Recessive Spondylocostal Dysostosis 4

Doid:0112364

Dysostosis, Spondylocostal, Autosomal Recessive, Type 4
Spondylocostal Dysostosis 1, Autosomal Recessive

Jarcho-Levin Syndrome

SCDO1

Vertebral Anomalies

Spondylothoracic Dysplasia

Costovertebral Dysplasia

Spondylothoracic Dysostosis

Spondylocostal Dysostosis 1

Autosomal Recessive Spondylocostal Dysostosis 1

Spondylocostal Dysostosis, Autosomal Recessive, 1

Doid:0112365

Dysostosis, Spondylocostal, Autosomal Recessive, Type 1
Spondylocostal Dysostosis

Jarcho-Levin Syndrome

Costovertebral Dysplasia

Spondylothoracic Dysostosis

Spondylothoracic Dysplasia

Scdo

Dysostosis, Spondylocostal
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08708 MSGN1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta MSGN1 VGNC VGNC:74771
Bos taurus MSGN1 VGNC VGNC:31692
Mus musculus MSGN1 MGD MGI:1860483
Rattus norvegicus MSGN1 RGD RGD:1587516
Canis familiaris MSGN1 VGNC VGNC:43437