MTX3 - metaxin 3 Gene

Homo sapiens

Gene ID: 345778 | Gene type: protein coding

About MTX3

Cytogenetic location: 5q14.1 Genomic coordinates (GRCh38): 5:79,976,716-79,991,262 (from NCBI)

This gene has 4 transcripts (splice variants), 201 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 5.4), thyroid (RPKM 5.2) and 25 other tissues.

Summary

Predicted to be involved in mitochondrion organization. Part of MIB complex and SAM complex. [provided by Alliance of Genome Resources, Apr 2022]

MTX3 Products(3)

mRNA	Protein	Name
NM_001010891.5	NP_001010891.4	metaxin-3 isoform 2
NM_001167741.2	NP_001161213.1	metaxin-3 isoform 1
NM_001363818.2	NP_001350747.1	metaxin-3 isoform 3

MTX3 Protein Structure

Tom37

Tom37_C

GST_C_3

0
100
200
312 a.a.

Protein Preferred Names

Protein Names

metaxin-3

Related Diseases

Diseases

Alias

Loeys-Dietz Syndrome 1

Furlong Syndrome	Loeys-Dietz Aortic Aneurysm Syndrome
LDS1	Aat5
Loeys-Dietz Syndrome Type 1	Aortic Aneurysm, Familial Thoracic 5
Familial Throacic Aortic Aneurysm 5	Loeys-Dietz Syndrome
Aortic Aneurysm Syndrome, Loeys-Dietz Type	Familial Thoracic Aortic Aneurysm 5
Ldas	Marfanoid Disorder-Craniosynostosis Syndrome
Aneurysm, Aortic, Thoracic, Familial, Type 5	Loeys-Dietz Syndrome, Type 1
Loeys-Dietz Syndrome, Type 2a

Transient Arthritis

Childhood Lymphoma

Pediatric Lymphoma

Robinow Syndrome, Autosomal Recessive 1

Robinow Syndrome, Autosomal Recessive	Autosomal Recessive Robinow Syndrome
Covesdem Syndrome	RRS1
Costovertebral Segmentation Defect-Mesomelia Syndrome	Rrs
Costovertebral Segmentation Defect With Mesomelia, Formerly	Covesdem Syndrome, Formerly
Costovertebral Segmentation Defect With Mesomelia	Robinow Syndrome Autosomal Recessive With Aplasia/Hypoplasia Of Phalanges And Metacarpals/Metatarsals
Robinow Syndrome Autosomal Recessive With Brachy-Syn-Polydactyly	Robinow Syndrome, Autosomal Recessive, With Aplasia/Hypoplasia Of Phalanges And Metacarpals/Metatarsals
Robinow Syndrome, Autosomal Recessive, With Brachy-Syn-Polydactyly	Robinow, Autosomal Recessive Syndrome, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08830	MTX3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	MTX3	VGNC	VGNC:84449
Canis familiaris	MTX3	VGNC	VGNC:53189
Mus musculus	MTX3	MGD	MGI:2686040
Rattus norvegicus	MTX3	RGD	RGD:1583002
Felis catus	MTX3	VGNC	VGNC:63663
Bos taurus	MTX3	VGNC	VGNC:55125