2. Gene
  3. APOC4 - apolipoprotein C4 Gene

APOC4 - apolipoprotein C4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as APO-CIV; APOC-IV

Gene ID: 346 | Gene type: protein coding

About APOC4

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:44,942,237-44,945,496 (from NCBI)

This gene has 2 transcripts (splice variants) and 77 orthologues. Restricted expression toward liver (RPKM 124.3).

Summary

This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene. [provided by RefSeq, Mar 2011]

APOC4 Products(1)

mRNA Protein Name
NM_001646.3 NP_001637.1 apolipoprotein C-IV precursor

APOC4 Protein Structure

APOC4

APOC4: Apolipoprotein C4 (27 - 125)

  • 0
  • 100
  • 127 a.a.
Protein Preferred Names Protein Names

apolipoprotein C-IV

Related Diseases

Diseases Alias
Hyperlipoproteinemia, Type Iv

Hyperlipoproteinemia Type Iv

Carbohydrate-Inducible Hyperlipemia

Endogenous Hyperlipidaemia

Familial Hypertriglyceridemia

Fredrickson Type Iv Hyperlipoproteinemia

Fredrickson Type Iv Lipidaemia

Fredrickson Type Iv Lipidemia

Vldl Hyperlipoproteinemia

Hyperlipoproteinemia Type 4

Carbohydrate Inducible Hyperlipemia

Familial Type Iv Hyperlipoproteinemia

Familial Hyperlipoproteinemia Type Iv
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00847 APOC4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus APOC4 MGD MGI:87878
Felis catus APOC4 VGNC VGNC:103060
Canis familiaris APOC4 VGNC VGNC:53523
Bos taurus APOC4 VGNC VGNC:52177
Macaca mulatta APOC4 VGNC VGNC:109594
Rattus norvegicus APOC4 RGD RGD:70959