2. Gene
  3. IGBP1 - immunoglobulin binding protein 1 Gene

IGBP1 - immunoglobulin binding protein 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as IBP1; MRXS28; alpha4; ALPHA-4

Gene ID: 3476 | Gene type: protein coding

About IGBP1

Cytogenetic location: Xq13.1 Genomic coordinates (GRCh38): X:70,133,447-70,166,324 (from NCBI)

This gene has 2 transcripts (splice variants), 236 orthologues, 1 paralogue and is associated with 4 phenotypes. Ubiquitous expression in ovary (RPKM 49.2), thyroid (RPKM 31.5) and 25 other tissues.

Summary

The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways. [provided by RefSeq, Jul 2008]

IGBP1 Products(4)

mRNA Protein Name
NM_001370192.1 NP_001357121.1 immunoglobulin-binding protein 1 isoform 1
NM_001370193.1 NP_001357122.1 immunoglobulin-binding protein 1 isoform 1
NM_001370194.1 NP_001357123.1 immunoglobulin-binding protein 1 isoform 2
NM_001551.3 NP_001542.1 immunoglobulin-binding protein 1 isoform 1

IGBP1 Protein Structure

TAP42

TAP42: TAP42-like family (12 - 329)

  • 0
  • 100
  • 200
  • 300
  • 339 a.a.
Protein Preferred Names Protein Names

immunoglobulin-binding protein 1

B cell signal transduction molecule alpha 4

Related Diseases

Diseases Alias
Corpus Callosum, Agenesis Of, With Impaired Intellectual Development, Ocular Coloboma, And Micrognathia

MRXS28

Mental Retardation, X-Linked, Syndromic 28

Intellectual Development Disorder, X-Linked, Syndromic 28

Corpus Callosum, Agenesis Of, With Impaired Intellectual Development, Ocular Coloboma And Micrognathia

Intellectual Developmental Disorder, X-Linked, Syndromic 28

Agenesis Of The Corpus Callosum With Impaired Intellectual Development, Ocular Coloboma And Micrognathia
Corpus Callosum Agenesis-Intellectual Disability-Coloboma-Micrognathia Syndrome

Graham-Cox Syndrome

Corpus Callosum, Agenesis Of, With Mental Retardation, Ocular Coloboma And Micrognathia

Mental Retardation, X-Linked, Syndromic 28

Mrxs28

Agenesis Of The Corpus Callosum-Intellectual Disability-Coloboma-Micrognathia Syndrome

Agenesis, Corpus Callosum, With Mental Retardation, Ocular Coloboma And Micrognathia

Corpus Callosum, Agenesis Of, With Mental Retardation, Ocular Coloboma, And Micrognathia
Barbiturate Abuse
Progressive Multifocal Leukoencephalopathy

Pml

Leukoencephalopathy, Progressive Multifocal

Progressive Multifocal Leukoencephalitis

Leukoencephalopathy Progressive Multifocal

Pml - [Progressive Multifocal Leukoencephalopathy]
Autosomal Dominant Alport Syndrome

Alport Syndrome, Autosomal Dominant

Alport Syndrome Dominant Type

Renal Failure And Sensorineural Hearing Loss

Alport Syndrome, Dominant Type
Autosomal Recessive Alport Syndrome

Alport Syndrome, Recessive Type

Alport Syndrome, Autosomal Recessive

Alport Syndrome Autosomal Recessive

Alport Syndrome Recessive Type

Nephropathy And Deafness
Hemoglobin H Disease

HBH

Hemoglobin H Disease, Nondeletional

Hemoglobin H Disease, Deletional

Alpha-Thalassemia Intermedia

Haemoglobin H Disease

Alpha-Thalassemia, Hemoglobin H Type

Hemoglobin H Disease, Deletional And Nondeletional

Alpha Thalassemia, Haemoglobin H Type

Alpha Thalassemia, Hemoglobin H Type

Haemoglobin H Disease, Deletional

Hbh Disease

Alpha-Thalassemia Hemoglobin H Type

Hemoglobin H Disease Deletional

Hemoglobin H Disease Non-Deletional

Alpha-Thalassemia

Alpha - /- - Or Mutational Forms Of Alpha-Thalassaemia

Alpha Thalassaemia Intermedia
Hypoalphalipoproteinemia, Primary, 2

Apolipoprotein A-I Deficiency

Hypoalphalipoproteinemia, Primary, 2, Autosomal Recessive

Primary Hypoalphalipoproteinemia 2

High Density Lipoprotein Deficiency

Apoa-I Deficiency

Familial Apoa-I Deficiency

Familial Hypoalphalipoproteinemia

FHA2

Apolipoprotein A-I
Alport Syndrome

Hereditary Nephritis

Alport Syndrome, X-Linked

Hemorrhagic Hereditary Nephritis

Congenital Hereditary Hematuria

Hemorrhagic Familial Nephritis

Familial Nephritis

Thin Basement Membrane Disease

Thin Basement Membrane Nephropathy

Hematuria-Nephropathy-Deafness Syndrome

Hematuric Hereditary Nephritis

Hereditary Familial Congenital Hemorrhagic Nephritis

Hereditary Hematuria Syndrome

Hereditary Interstitial Pyelonephritis

Alport Deafness-Nephropathy

Alport Hearing Loss-Nephropathy

Alports Syndrome

Nephritis, Hereditary
Autosomal Dominant Nocturnal Frontal Lobe Epilepsy

Adnfle

Autosomal Dominant Sleep-Related Hypermotor Epilepsy

Enfl

Benign Familial Infantile Seizures 6

Benign Familial Infantile Seizures, 6

Nocturnal Frontal Lobe Epilepsy-4

Enfl1

Epilepsy, Nocturnal Frontal Lobe, 1

Epilepsy, Nocturnal Frontal Lobe, Type 1
Alpha-Thalassemia

Alpha Thalassemia

Alpha Thalassaemia

Alpha Plus Thalassemia

Thalassemia, Alpha-

Thalassemias, Alpha-

A-Thalassemia

Α-Thalassemia

A-THAL

Thalassemia

Alpha Thalassaemia Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06612 IGBP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris IGBP1 VGNC VGNC:54166
Rattus norvegicus IGBP1 RGD RGD:62011
Mus musculus IGBP1 MGD MGI:1346500