Ikbke - inhibitor of nuclear factor kappa B kinase subunit epsilon Gene

Rattus norvegicus

Gene ID: 363984 | Gene type: protein coding

About Ikbke

Primary_assembly 13: 42,712,159-42,737,143 reverse strand.mRatBN7.2:CM026986.1

This gene has 1 transcript (splice variant), 199 orthologues, 3 paralogues and is associated with 3 phenotypes. Biased expression in Thymus (RPKM 144.4), Spleen (RPKM 1.1) and 9 other tissues.

Summary

Predicted to enable several functions, including IkappaB kinase activity; K48-linked polyubiquitin modification-dependent protein binding activity; and NF-kappaB-inducing kinase activity. Predicted to be involved in several processes, including interleukin-17-mediated signaling pathway; positive regulation of signal transduction; and regulation of RNA metabolic process. Predicted to be located in PML body and mitochondrial membrane. Predicted to be active in cytoplasm. Orthologous to human IKBKE (inhibitor of nuclear factor kappa B kinase subunit epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Ikbke Products(1)

mRNA	Protein	Name
NM_001108854.1	NP_001102324.1	inhibitor of nuclear factor kappa-B kinase subunit epsilon

Ikbke Protein Structure

PKc_like

Ubl_IKKE

TBK1_CCD1

0
200
400
600
719 a.a.

Protein Preferred Names

Protein Names

inhibitor of nuclear factor kappa-B kinase subunit epsilon

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon

inhibitor of kappaB kinase epsilon

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-D0162	Malachite green hemioxalate		≥98.0%	Unkown
HY-RS06661	IKBKE Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS06662	Ikbke Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS06663	Ikbke Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ikbke	NCBI	NCBI:9641

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