INSM1 - INSM transcriptional repressor 1 Gene

Homo sapiens

Also known as IA1; IA-1

Gene ID: 3642 | Gene type: protein coding

About INSM1

Cytogenetic location: 20p11.23 Genomic coordinates (GRCh38): 20:20,368,104-20,370,949 (from NCBI)

This gene has 1 transcript (splice variant), 210 orthologues and 1 paralogue.

Summary

Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors. [provided by RefSeq, Jul 2008]

INSM1 Products(1)

mRNA	Protein	Name
NM_002196.3	NP_002187.1	insulinoma-associated protein 1

INSM1 Protein Structure

zf-C2H2

zf-C2H2_4

zf-C2H2

0
100
200
300
400
510 a.a.

Protein Preferred Names

Protein Names

insulinoma-associated protein 1

insulinoma-associated 1

Related Diseases

Diseases

Alias

Insulinoma

Islet Cell Adenoma	Insulin-Producing Tumor Of Islet Cells
Adenoma Islet Cell	Islet Cell Tumor
Experimental Organism Islet Cell Adenoma Neoplasm

Neuroendocrine Tumor

Neuroendocrine Neoplasm	Neuroendocrine Tumors
Carcinoma, Neuroendocrine

Early Invasive Cervical Adenocarcinoma

Microinvasive Cervical Squamous Cell Carcinoma

Early Invasive Cervical Squamous Cell Carcinoma

Papillary Squamous Carcinoma

Papillary Epidermoid Carcinoma

Papillary Squamous Cell Carcinoma

Urinary Bladder Small Cell Neuroendocrine Carcinoma

Small Cell Neuroendocrine Carcinoma Of The Urinary Bladder

Small Cell/Neuroendocrine Carcinoma Of Urinary Bladder

Uterus Carcinoma In Situ

Ethmoid Sinus Cancer

Malignant Neoplasm Of Ethmoidal Sinus	Malignant Tumor Of Ethmoid Sinus
Malignant Tumor Of Ethmoidal Sinus	Neoplasm Of Ethmoidal Sinus

Cervical Incompetence

Uterine Cervical Incompetence

Hemometra

Hematometra

Cervix Uteri Carcinoma In Situ

Carcinoma In Situ Of Cervix	Carcinoma In Situ Of Uterine Cervix
Cervical Intraepithelial Neoplasia	Carcinoma Of Cervix Stage 0
Cervical Intraepithelial Neoplasia Grade Iii With Severe Dysplasia	Cervix Ca In Situ
Cin Iii	Cin Iii - Carcinoma In Situ Of Cervix
Cin Iii - Severe Dyskaryosis	Severe Dysplasia Of Cervix
Severe Dysplasia Of The Cervix Uteri	Squamous Intraepithelial Neoplasia, Grade Iii
Cervix Intraepithelial Neoplasia Grade 3 Ajcc V7

Vaginal Cancer

Malignant Neoplasm Of Vagina	Vaginal Neoplasms
Malignant Tumor Of Vagina	Malignant Vaginal Tumor
Neoplasm Of Vagina	Vagina Neoplasm
Vaginal Tumor	Vaginal Carcinoma
Vaginal Malignant Epithelial Tumor	Vaginal Neoplasm
Malignant Vaginal Neoplasm	Vagina Carcinoma
Vaginal Neoplasia	Cancer Of Vagina
Malignant Tumour Of Vagina	Carcinoma Of Vagina
Primary Malignant Neoplasm Of Vagina	Vagina Wall Cancer
Vaginal Wall Cancer

Adenocarcinoma In Situ

Isthmus Cancer

Sweat Gland Cancer

Sweat Gland Carcinoma	Malignant Neoplasm Of Sweat Gland
Malignant Tumor Of The Sweat Gland	Carcinoma Of The Sweat Gland
Primary Malignant Neoplasm Of Sweat Gland	Sweat Gland Neoplasms

Lymphocele

Lymph Cyst

Lymphocele Adverse Event

Bleeding Disorder, Platelet-Type, 17

Platelet-Type Bleeding Disorder 17	BDPLT17
Thrombasthenia-Thrombocytopenia, Hereditary	Hereditary Thrombasthenia-Thrombocytopenia
Autosomal Dominant Macrothrombocytopenia Gfi1b-Related	Autosomal Dominant Platelet Disorder Gfi1b-Related
Bleeding Disorder, Platelet Type 17

Small Cell Cancer Of The Lung

Small Cell Lung Cancer	Small Cell Lung Carcinoma
Sclc	Small-Cell Cancer Of Lung
Lung Small Cell Carcinoma	Sclc1
Sccl	Cancer, Lung, Small Cell
Small Cell Carcinoma Of Lung	Carcinoma, Small Cell

Hidrocystoma

Apocrine Cystadenoma	Eccrine Hidrocystoma
Eccrine Cystadenoma	Eccrine Hidrocystoma Of Skin
Apocrine Adenoma

Pulmonary Neuroendocrine Tumor

Neuroendocrine Neoplasm Of Lung

Large Cell Neuroendocrine Carcinoma

Fallopian Tube Endometrioid Adenocarcinoma

Endometrioid Carcinoma Of The Fallopian Tube	Fallopian Tube Endometrioid Cancer
Fallopian Tube Endometrioid Neoplasm	Fallopian Tube Endometrioid Tumor

Adenosquamous Carcinoma

Adenosquamous Cell Carcinoma	Mixed Adenocarcinoma And Squamous Carcinoma
Carcinoma Adenosquamous	Carcinoma, Adenosquamous

Lung Large Cell Carcinoma

Large Cell Carcinoma Of Lung	Large Cell Lung Carcinoma
Large Cell Lung Cancer

Pulmonary Large Cell Neuroendocrine Carcinoma

Large Cell Lung Neuroendocrine Carcinoma

Basaloid Squamous Cell Carcinoma

Basaloid Carcinoma

Endocervical Carcinoma

Carcinoma Of Endocervix

Carcinoma Of The Endocervix

Cervical Adenocarcinoma

Adenocarcinoma Cervix Uteri	Adenocarcinoma Of Cervix
Adenocarcinoma Of The Uterine Cervix	Adenocarcinoma Of The Cervix Uteri

Chronic Cervicitis

Paranasal Sinus Cancer

Paranasal Sinus Adenoid Cystic Carcinoma	Paranasal Sinus Mucoepidermoid Carcinoma
Paranasal Sinus Squamous Cell Carcinoma	Paranasal Sinus Neoplasms
Adenoid Cystic Carcinoma Of Accessory Sinus	Adenoid Cystic Carcinoma Of Paranasal Sinus
Epidermoid Carcinoma Of The Paranasal Sinus	Mucoepidermoid Carcinoma Of Accessory Sinus
Paranasal Sinus Adenocarcinoma	Squamous Cell Carcinoma Of Paranasal Sinus
Paranasal Sinus Neoplasm	Adenocarcinoma Of Accessory Sinus

Cervix Carcinoma

Cancer Of Cervix	Carcinoma Of Cervix
Carcinoma Cervix Uteri	Carcinoma Of The Cervix Uteri

Sebaceous Gland Disease

Sebaceous Gland Anomaly

Sebaceous Gland Diseases

Endocervical Adenocarcinoma

Endocervical Carcinoma

Pancreatic Cystadenoma

Cystadenoma Of Pancreas

Pheochromocytoma

Pheochromocytoma, Susceptibility To	Phaeochromocytoma
Adrenal Gland Chromaffin Paraganglioma	Adrenal Gland Chromaffinoma
Adrenal Gland Paraganglioma	Adrenal Gland Pheochromocytoma
Chromaffin Paraganglioma Of The Adrenal Gland	Intraadrenal Paraganglioma
PCC	Chromaffin Cell Tumor
Medullary Chromaffinoma	Medullary Paraganglioma
Pheochromoblastoma	Pheochromocytomas
Chromaffin Cell Neoplasm	Pheochromocytoma, Malignant

In Situ Carcinoma

Carcinoma In Situ

Pre-Malignant Neoplasm

Chondrosarcoma, Extraskeletal Myxoid

Extraskeletal Myxoid Chondrosarcoma	Emc
Myxoid Extraosseous Chondrosarcoma

Medulloblastoma

MDB	Cpnet
Localized Primitive Neuroectodermal Tumor	Classic Medulloblastoma
Medulloblastoma Predisposition Syndrome	Medulloblastoma, Somatic
Brain Medulloblastoma	Cns Pnet
Infratentorial Primitive Neuroectodermal Tumor	Neuroectodermal Tumors, Primitive
Medulloblastomas	Desmoplastic Medulloblastoma
Medulloblastoma, With Extensive Nodularity	Medulloblastoma Of Unspecified Site
Medullomyoblastoma Of Unspecified Site

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06844	INSM1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	INSM1	MGD	MGI:1859980
Bos taurus	INSM1	VGNC	VGNC:30220
Macaca mulatta	INSM1	VGNC	VGNC:84917
Rattus norvegicus	INSM1	RGD	RGD:6486258