STIMATE - STIM activating enhancer Gene

Homo sapiens

Also known as TMEM110

Gene ID: 375346 | Gene type: protein coding

About STIMATE

Cytogenetic location: 3p21.1 Genomic coordinates (GRCh38): 3:52,836,733-52,897,548 (from NCBI)

This gene has 6 transcripts (splice variants), 194 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 12.1), lung (RPKM 12.0) and 25 other tissues.

Summary

Enables Calcium Channel regulator activity. Involved in activation of store-operated Calcium Channel activity; calcium-mediated signaling using intracellular calcium source; and positive regulation of calcineurin-NFAT signaling cascade. Located in cortical endoplasmic reticulum; endoplasmic reticulum membrane; and endoplasmic reticulum-plasma membrane contact site. [provided by Alliance of Genome Resources, Apr 2022]

STIMATE Products(1)

mRNA	Protein	Name
NM_198563.5	NP_940965.1	store-operated calcium entry regulator STIMATE

STIMATE Protein Structure

STIMATE

0
100
200
294 a.a.

Protein Preferred Names

Protein Names

store-operated calcium entry regulator STIMATE

STIM-activating enhancer encoded by TMEM110

Related Diseases

Diseases

Alias

Stormorken Syndrome

Thrombocytopathy, Asplenia, And Miosis	Stormorken-Sjaastad-Langslet Syndrome
STRMK	York Platelet Syndrome
Yps	Thrombocytopathy, Asplenia And Miosis
Thrombocytopathy Asplenia Miosis	Thrombocytopathy-Asplenia-Miosis Syndrome
Miosis Disorder

Capgras Syndrome

Capgras Delusion Theory

Cenani-Lenz Syndactyly Syndrome

Syndactyly Type 7	Cenani Syndactylism
Cenani-Lenz Syndactyly	CLSS
Syndactyly Cenani Lenz Type	Cenani-Lenz Syndrome
Syndactyly, Type Vii	Cenani-Lenz Type Syndactyly
Cenani Syndactyly	Syndactyly Type Vii

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13915	STIMATE Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	STIMATE	MGD	MGI:1921500

Name
Email *

	Sorry, but the email address you supplied was invalid.