2. Gene
  3. KCNG1 - potassium voltage-gated channel modifier subfamily G member 1 Gene

KCNG1 - potassium voltage-gated channel modifier subfamily G member 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as K13; kH2; KCNG; KV6.1

Gene ID: 3755 | Gene type: protein coding

About KCNG1

Cytogenetic location: 20q13.13 Genomic coordinates (GRCh38): 20:51,003,656-51,023,107 (from NCBI)

This gene has 6 transcripts (splice variants), 197 orthologues and 31 paralogues. Biased expression in endometrium (RPKM 3.9), placenta (RPKM 2.0) and 11 other tissues.

Summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, Insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the Potassium Channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008]

KCNG1 Products(1)

mRNA Protein Name
NM_002237.4 NP_002228.2 potassium voltage-gated channel subfamily G member 1

KCNG1 Protein Structure

BTB_2

BTB_2: BTB/POZ domain (65 - 164)

Ion_trans

Ion_trans: Ion transport protein (270 - 456)

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  • 513 a.a.
Protein Preferred Names Protein Names

potassium voltage-gated channel subfamily G member 1

potassium channel KH2

Related Diseases

Diseases Alias
Coumarin Resistance

Warfarin Resistance

Warfarin Sensitivity

Coumadin Sensitivity

Warfarin Response

Poor Metabolism Of Coumarin

Coumarin, Poor Metabolism Of

CMRES
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07121 KCNG1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus KCNG1 VGNC VGNC:30442
Mus musculus KCNG1 MGD MGI:3616086
Rattus norvegicus KCNG1 RGD RGD:631416
Macaca mulatta KCNG1 VGNC VGNC:73979
Canis familiaris KCNG1 VGNC VGNC:42245
Felis catus KCNG1 VGNC VGNC:67906