KIFC3 - kinesin family member C3 Gene

Homo sapiens

Gene ID: 3801 | Gene type: protein coding

About KIFC3

Cytogenetic location: 16q21 Genomic coordinates (GRCh38): 16:57,758,217-57,862,858 (from NCBI)

This gene has 35 transcripts (splice variants), 202 orthologues and 41 paralogues. Broad expression in kidney (RPKM 11.2), testis (RPKM 9.9) and 24 other tissues.

Summary

This gene encodes a member of the Kinesin-14 family of microtubule motors. Members of this family play a role in the formation, maintenance and remodeling of the bipolar mitotic spindle. The protein encoded by this gene has cytoplasmic functions in the interphase cells. It may also be involved in the final stages of cytokinesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

KIFC3 Products(9)

mRNA	Protein	Name
NM_001130099.1	NP_001123571.1	kinesin-like protein KIFC3 isoform 3
NM_001130100.2	NP_001123572.1	kinesin-like protein KIFC3 isoform 2
NM_001318710.2	NP_001305639.1	kinesin-like protein KIFC3 isoform 4
NM_001318711.2	NP_001305640.1	kinesin-like protein KIFC3 isoform 5
NM_001318712.2	NP_001305641.1	kinesin-like protein KIFC3 isoform 6
NM_001318713.2	NP_001305642.1	kinesin-like protein KIFC3 isoform 7
NM_001318714.2	NP_001305643.1	kinesin-like protein KIFC3 isoform 3
NM_001318715.2	NP_001305644.1	kinesin-like protein KIFC3 isoform 3
NM_005550.4	NP_005541.3	kinesin-like protein KIFC3 isoform 1

KIFC3 Protein Structure

Kinesin

0
200
400
600
833 a.a.

Protein Preferred Names

Protein Names

kinesin-like protein KIFC3

Related Diseases

Diseases

Alias

Retinitis Pigmentosa 63

RP63

Optic Atrophy 8

OPA8

Fanconi Anemia, Complementation Group C

Fanconi Anemia Complementation Group C	FANCC
Facc	Fac
Fa3	Fanconi Pancytopenia Type 3
Fanconi Pancytopenia, Type 3	Faces Syndrome
Facial Features , Anorexia, Cachexia, Eye And Skin Anomalies	Friedman-Goodman Syndrome
Abnormality Of The Face

Zellweger Syndrome

Cerebrohepatorenal Syndrome	Zellweger Leukodystrophy
Zs	Congenital Iron Overload
Chr	Zws
Severe Pbd-Zsd	Severe Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07300	KIFC3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	KIFC3	VGNC	VGNC:42416
Rattus norvegicus	KIFC3	RGD	RGD:1307693
Felis catus	KIFC3	VGNC	VGNC:67947
Mus musculus	KIFC3	MGD	MGI:109202
Macaca mulatta	KIFC3	VGNC	VGNC:74022
Bos taurus	KIFC3	VGNC	VGNC:30613

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