RNF207 - ring finger protein 207 Gene

Homo sapiens

Also known as C1orf188

Gene ID: 388591 | Gene type: protein coding

About RNF207

Cytogenetic location: 1p36.31 Genomic coordinates (GRCh38): 1:6,206,119-6,221,299 (from NCBI)

This gene has 9 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in heart (RPKM 5.9), prostate (RPKM 3.0) and 24 other tissues.

Summary

Enables HSP70 protein binding activity; chaperone binding activity; and transmembrane transporter binding activity. Involved in positive regulation of delayed rectifier Potassium Channel activity; positive regulation of gene expression; and positive regulation of voltage-gated Potassium Channel activity involved in ventricular cardiac muscle cell action potential repolarization. Located in perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RNF207 Products(1)

mRNA	Protein	Name
NM_207396.3	NP_997279.2	RING finger protein 207

RNF207 Protein Structure

zf-C3HC4

zf-B_box

0
100
200
300
400
500
634 a.a.

Protein Preferred Names

Protein Names

RING finger protein 207

Related Diseases

Diseases

Alias

Long Qt Syndrome

Romano-Ward Syndrome	Long Q-T Syndrome
Lqt	Qt Syndrome, Long
Congenital Long Qt Syndrome	Familial Long Qt Syndrome

Posterior Myocardial Infarction

Brugada Syndrome

Sudden Unexpected Nocturnal Death Syndrome	Sudden Unexplained Nocturnal Death Syndrome
Bangungut	Brugada Type Idiopathic Ventricular Fibrillation
Pokkuri Death Syndrome	Sunds
Idiopathic Ventricular Fibrillation, Brugada Type	Sudden Unexplained Death
Dream Disease	Right Bundle Branch Block, St Segment Elevation, And Sudden Death Syndrome
Sudden Unexplained Death Syndrome	Suds
Sunds - [Sudden Unexplained Nocturnal Death Syndrome]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12076	RNF207 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	RNF207	VGNC	VGNC:64690
Bos taurus	RNF207	VGNC	VGNC:34048
Canis familiaris	RNF207	VGNC	VGNC:45654
Macaca mulatta	RNF207	VGNC	VGNC:100061
Rattus norvegicus	RNF207	RGD	RGD:1586262
Mus musculus	RNF207	MGD	MGI:2684989

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