MFSD2B - MFSD2 lysolipid transporter B, sphingolipid Gene

Homo sapiens

Also known as SLC59A2

Gene ID: 388931 | Gene type: protein coding

About MFSD2B

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:24,010,085-24,026,775 (from NCBI)

This gene has 6 transcripts (splice variants), 210 orthologues and 2 paralogues. Biased expression in bone marrow (RPKM 2.9), placenta (RPKM 0.3) and 1 other tissue.

Summary

Enables sphingolipid transporter activity. Involved in lipid transport. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

MFSD2B Products(1)

mRNA	Protein	Name
NM_001346880.2	NP_001333809.1	sphingosine-1-phosphate transporter MFSD2B

MFSD2B Protein Structure

MFS_2

0
100
200
300
400
497 a.a.

Protein Preferred Names

Protein Names

sphingosine-1-phosphate transporter MFSD2B

S1P transporter

Related Diseases

Diseases

Alias

Seckel Syndrome 1

SCKL1	Nanocephalic Dwarfism
Microcephalic Primordial Dwarfism I	Seckel-Type Dwarfism
Bird-Headed Dwarfism	Sckl
Seckel Syndrome, Type 1	Seckel Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08392	MFSD2B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	MFSD2B	VGNC	VGNC:31436
Canis familiaris	MFSD2B	VGNC	VGNC:43201
Macaca mulatta	MFSD2B	VGNC	VGNC:74636
Rattus norvegicus	MFSD2B	RGD	RGD:1561716
Mus musculus	MFSD2B	MGD	MGI:3583946
Felis catus	MFSD2B	VGNC	VGNC:63480

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