2. Gene
  3. RND3 - Rho family GTPase 3 Gene

RND3 - Rho family GTPase 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ARHE; Rho8; RhoE; memB

Gene ID: 390 | Gene type: protein coding

About RND3

Cytogenetic location: 2q23.3 Genomic coordinates (GRCh38): 2:150,468,193-150,487,695 (from NCBI)

This gene has 9 transcripts (splice variants), 264 orthologues and 22 paralogues. Broad expression in esophagus (RPKM 87.1), liver (RPKM 49.1) and 19 other tissues.

Summary

This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]

RND3 Products(2)

mRNA Protein Name
NM_001254738.1 NP_001241667.1 rho-related GTP-binding protein RhoE precursor
NM_005168.5 NP_005159.1 rho-related GTP-binding protein RhoE precursor

RND3 Protein Structure

Ras

Ras: Ras family (25 - 193)

  • 0
  • 100
  • 200
  • 244 a.a.
Protein Preferred Names Protein Names

rho-related GTP-binding protein RhoE

protein MemB

Related Diseases

Diseases Alias
Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma
Hydrocephalus

Hydrocephalus, Nonsyndromic, Autosomal Recessive

Hydrocephalus, X-Linked

Hydrocephalus Adverse Event

Hydrocephaly Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12033 RND3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RND3 VGNC VGNC:45618
Rattus norvegicus RND3 RGD RGD:1359690
Mus musculus RND3 MGD MGI:1921444
Macaca mulatta RND3 VGNC VGNC:76883
Felis catus RND3 VGNC VGNC:68099
Bos taurus RND3 VGNC VGNC:34006