2. Gene
  3. KDM4E - lysine demethylase 4E Gene

KDM4E - lysine demethylase 4E Gene

  • Gene
  • Protein
  • Agent
Homo sapiens

Also known as KDM5E; JMJD2E; KDM4DL

Gene ID: 390245 | Gene type: protein coding

About KDM4E

Cytogenetic location: 11q21 Genomic coordinates (GRCh38): 11:95,025,258-95,027,596 (from NCBI)

This gene has 1 transcript (splice variant), 97 orthologues and 10 paralogues.

Summary

The protein encoded by this intronless gene is a member of a large family of histone lysine demethylases, which use oxygen and 2-oxoglutarate to demethylate di- and trimethylated lys9 of histone H3. Derepression of genes by demethylases is sometimes involved in viral Infection or carcinogenesis, so inhibitors of these enzymes are desired. [provided by RefSeq, Dec 2016]

KDM4E Products(1)

mRNA Protein Name
NM_001161630.1 NP_001155102.1 lysine-specific demethylase 4E

KDM4E Protein Structure

JmjN

JmjN: jmjN domain (16 - 50)

JmjC

JmjC: JmjC domain, hydroxylase (176 - 292)

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  • 506 a.a.
Protein Preferred Names Protein Names

lysine-specific demethylase 4E

KDM4D-like protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12304 IOX1 Inhibitor 99.72% Unkown
HY-RS07217 KDM4E Human Pre-designed siRNA Set A Pre-designed Sets / Unkown