1. Gene
  2. LGALS9 - galectin 9 Gene

LGALS9 - galectin 9 Gene

Homo sapiens

Also known as HUAT; LGALS9A

Gene ID: 3965 | Gene type: protein coding

About LGALS9

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:27,631,188-27,649,560 (from NCBI)

This gene has 16 transcripts (splice variants), 353 orthologues and 16 paralogues. Broad expression in spleen (RPKM 33.5), stomach (RPKM 28.4) and 23 other tissues.

Summary

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

LGALS9 Products(3)

mRNA Protein Name
NM_001330163.2 NP_001317092.1 galectin-9 isoform 3
NM_002308.4 NP_002299.2 galectin-9 isoform short
NM_009587.3 NP_033665.1 galectin-9 isoform long

LGALS9 Protein Structure

Gal-bind_lectin

Gal-bind_lectin: Galactoside-binding lectin (16 - 146)

Gal-bind_lectin

Gal-bind_lectin: Galactoside-binding lectin (226 - 354)

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  • 200
  • 300
  • 355 a.a.
Protein Preferred Names Protein Names

galectin-9

ecalectin

Recombinant LGALS9 Proteins

Related Diseases

Diseases Alias
Dengue Virus

Dengue Virus, Susceptibility To

Dengue Fever, Protection Against

Dengue Fever

Patulous Eustachian Tube

Pet

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus LGALS9 RGD RGD:3005
Mus musculus LGALS9 MGD MGI:109496
Others LGALS9 NCBI