2. Gene
  3. ART1 - ADP-ribosyltransferase 1 Gene

ART1 - ADP-ribosyltransferase 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RT6; ART2; ARTC1; CD296

Gene ID: 417 | Gene type: protein coding

About ART1

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:3,645,128-3,664,416 (from NCBI)

This gene has 2 transcripts (splice variants), 652 orthologues and 3 paralogues. Low expression observed in reference dataset.

Summary

ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of Bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008]

ART1 Products(1)

mRNA Protein Name
NM_004314.3 NP_004305.2 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 precursor

ART1 Protein Structure

ART

ART: NAD:arginine ADP-ribosyltransferase (39 - 274)

  • 0
  • 100
  • 200
  • 300
  • 327 a.a.
Protein Preferred Names Protein Names

GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1

ADP-ribosyltransferase 2

Related Diseases

Diseases Alias
Type 1 Diabetes Mellitus 8

Diabetes Mellitus, Insulin-Dependent, 8

Iddm8

Insulin-Dependent Diabetes Mellitus 8

T1D8

Insulin-Dependent Diabetes Mellitus-8
Lutembacher'S Syndrome

Lutembacher Syndrome

Lutembacher'S Anomaly
Lateral Myocardial Infarction
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01044 ART1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ART1 MGD MGI:107511
Felis catus ART1 VGNC VGNC:68316
Canis familiaris ART1 VGNC VGNC:38147
Rattus norvegicus ART1 RGD RGD:1304591
Macaca mulatta ART1 VGNC VGNC:70024
Macaca fascicularis ART1 NCBI
Others ART1 NCBI