ART3 - ADP-ribosyltransferase 3 (inactive) Gene

Homo sapiens

Also known as ARTC3

Gene ID: 419 | Gene type: protein coding

About ART3

Cytogenetic location: 4q21.1 Genomic coordinates (GRCh38): 4:76,011,190-76,112,786 (from NCBI)

This gene has 17 transcripts (splice variants), 582 orthologues and 3 paralogues. Biased expression in testis (RPKM 18.7) and heart (RPKM 6.2).

Summary

This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

ART3 Products(16)

mRNA	Protein	Name
NM_001130016.3	NP_001123488.1	ecto-ADP-ribosyltransferase 3 isoform a precursor
NM_001130017.3	NP_001123489.1	ecto-ADP-ribosyltransferase 3 isoform c precursor
NM_001179.6	NP_001170.2	ecto-ADP-ribosyltransferase 3 isoform b precursor
NM_001377173.1	NP_001364102.1	ecto-ADP-ribosyltransferase 3 isoform d precursor
NM_001377174.1	NP_001364103.1	ecto-ADP-ribosyltransferase 3 isoform l precursor
NM_001377175.1	NP_001364104.1	ecto-ADP-ribosyltransferase 3 isoform c precursor
NM_001377176.1	NP_001364105.1	ecto-ADP-ribosyltransferase 3 isoform e precursor
NM_001377177.1	NP_001364106.1	ecto-ADP-ribosyltransferase 3 isoform f precursor
NM_001377178.1	NP_001364107.1	ecto-ADP-ribosyltransferase 3 isoform f precursor
NM_001377179.1	NP_001364108.1	ecto-ADP-ribosyltransferase 3 isoform g precursor
NM_001377180.1	NP_001364109.1	ecto-ADP-ribosyltransferase 3 isoform h precursor
NM_001377181.1	NP_001364110.1	ecto-ADP-ribosyltransferase 3 isoform i precursor
NM_001377182.1	NP_001364111.1	ecto-ADP-ribosyltransferase 3 isoform i precursor
NM_001377183.1	NP_001364112.1	ecto-ADP-ribosyltransferase 3 isoform j precursor
NM_001377184.1	NP_001364113.1	ecto-ADP-ribosyltransferase 3 isoform j precursor
NM_001377185.1	NP_001364114.1	ecto-ADP-ribosyltransferase 3 isoform k precursor

ART3 Protein Structure

ART

0
100
200
300
389 a.a.

Protein Preferred Names

Protein Names

ecto-ADP-ribosyltransferase 3

ADP-ribosyltransferase C2 and C3 toxin-like 3

Recombinant ART3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P74409	ART3 Protein, Human (HEK293, His)	AAH08397 (M1-S362)	≥95%

Related Diseases

Diseases

Alias

Lumbosacral Lipoma

Hypermobility Of Coccyx

Coccygeal Hypermobility Syndrome

Hypermobility Of The Coccyx

Afferent Loop Syndrome

Afferent Limb Syndrome

Klippel-Feil Syndrome 3

Placenta Praevia

Placenta Previa	Haemorrhage From Placenta Previa
Placenta Previa Haemorrhage	Lateral Placenta
Low Implantation Of Placenta Nos Or With Haemorrhage	Total Placenta Previa
Total Placenta Praevia Nos Or With Haemorrhage	Placental Previa Haemorrhage
Pp - [Placenta Previa]	Placenta Previa Marginalis
Placenta Previa Partialis	Partial Placenta Previa
Placenta Previa Centralis	Low Implantation Of Placenta
Low Implantation Or Insertion Of Placenta	Low Insertion Of Placenta
Low Lying Placenta	Marginal Placenta
Marginal Placenta Praevia Nos Or With Haemorrhage	Marginal Placenta Previa
Marginal Placental Haemorrhage	Partial Placenta Praevia Nos Or With Haemorrhage

Kummell'S Disease

Traumatic Spondylopathy	Kummell Disease
Kummell'S Spondylitis	Kümmelll-Verneuil Disease
Kümmell Spondylitis	Kümmell Disease
Traumatic Spondylosis

Brown-Sequard Syndrome

Brown-Squard Syndrome	Hemicord Syndrome
Hemiparaplegic Syndrome	Hemispinal Cord Syndrome
Brown-Séquard Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01045	ART3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ART3	MGD	MGI:1202729
Rattus norvegicus	ART3	RGD	RGD:628833
Felis catus	ART3	VGNC	VGNC:68318
Bos taurus	ART3	VGNC	VGNC:26180
Canis familiaris	ART3	VGNC	VGNC:38148
Macaca mulatta	ART3	VGNC	VGNC:70025
Others	ART3	NCBI