MYBL1 - MYB proto-oncogene like 1 Gene

Homo sapiens

Also known as AMYB; A-MYB

Gene ID: 4603 | Gene type: protein coding

About MYBL1

Cytogenetic location: 8q13.1 Genomic coordinates (GRCh38): 8:66,562,175-66,613,218 (from NCBI)

This gene has 6 transcripts (splice variants), 222 orthologues and 6 paralogues. Broad expression in lymph node (RPKM 9.0), testis (RPKM 6.1) and 15 other tissues.

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MYBL1 Products(3)

mRNA	Protein	Name
NM_001080416.4	NP_001073885.1	myb-related protein A isoform 1
NM_001144755.3	NP_001138227.1	myb-related protein A isoform 2
NM_001294282.2	NP_001281211.1	myb-related protein A isoform 3

MYBL1 Protein Structure

Myb_DNA-bind_6

Myb_DNA-binding

LMSTEN

Cmyb_C

0
200
400
600
752 a.a.

Protein Preferred Names

Protein Names

myb-related protein A

myb-like protein 1

Related Diseases

Diseases

Alias

Adenoid Cystic Carcinoma

Adenocystic Carcinoma	Cribriform Carcinoma
Cylindroma	Carcinoma Adenoid Cystic
Carcinoma, Adenoid Cystic	Adenoid Cystic Carcinoma Of Salivary Gland
Eccrine Dermal Cylindroma	Carcinoma, Cribriform

Thalamic Neoplasm

Malignant Neoplasm Of Thalamus	Malignant Tumor Of Thalamus
Tumor Of Thalamus

Bartholin'S Gland Adenoid Cystic Carcinoma

Bartholin Gland Adenoid Cystic Carcinoma

Breast Adenoid Cystic Carcinoma

Adenoid Cystic Breast Carcinoma	Adenoid Cystic Carcinoma Of Breast
Mammary Adenocystic Carcinoma

Dysembryoplastic Neuroepithelial Tumor

Dysembryoplastic Neuroepithelial Tumour	Dysembryoplastic Neuroepithelial Neoplasm
Dnet

Tonsil Cancer

Tonsillar Neoplasms	Malignant Neoplasm Of Faucial Tonsil
Malignant Neoplasm Of Palatine Tonsil	Malignant Neoplasm Of Tonsil, Faucial
Malignant Tonsillar Tumor	Malignant Tumor Of Tonsil
Tonsillar Carcinoma	Malignant Neoplasm Tonsil

Eccrine Papillary Adenocarcinoma

Digital Papillary Adenocarcinoma	Sweat Gland Adenocarcinoma
Digital Papillary Eccrine Carcinoma Of Skin

Cutaneous Adenocystic Carcinoma

Adenoid Cystic Eccrine Carcinoma	Adenoid Cystic Carcinoma Of The Skin
Adenoid Cystic Eccrine Carcinoma Of Skin

Diffuse Astrocytoma

Diffuse Astrocytoma, Low Grade	Who Grade Ii Astrocytoma
Fibrillary Astrocytoma	Gemistocytic Astrocytoma
Low-Grade Diffuse Astrocytoma	Protoplasmic Astrocytoma

Salivary Gland Carcinoma

Salivary Gland Cancer	Malignant Neoplasm Of Salivary Gland
Salivary Gland Neoplasms

Chordoid Glioma

Chordoid Glioma Of The Third Ventricle

Oropharynx Cancer

Oropharyngeal Cancer	Oropharyngeal Carcinoma
Malignant Neoplasm Of Oropharynx	Malignant Oropharyngeal Tumor
Malignant Tumor Of Oropharynx	Malignant Tumour Of Mesopharynx
Oropharyngeal Cancer, Adult	Cancer Of The Oropharynx

Lung Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma Of Lung

Pulmonary Adenoid Cystic Carcinoma

Eccrine Adenocarcinoma

Pleomorphic Xanthoastrocytoma

Pxa	Pleomorphic Xantho-Astrocytoma

Ceruminoma

Ceruminous Adenoma

External Auditory Canal Ceruminous Adenoma

Salivary Gland Adenoid Cystic Carcinoma

Cylindroma

Cerebellar Liponeurocytoma

Lipomatous Medulloblastoma

Central Neurocytoma

Breast Mucoepidermoid Carcinoma

Mucoepidermoid Carcinoma Of Breast

Mucoepidermoid Carcinoma Of The Breast

Ceruminous Adenocarcinoma

Pilomyxoid Astrocytoma

Childhood Oligodendroglioma

Pediatric Oligodendroglioma

Oligodendroglioma, Childhood

Astroblastoma

Cerebral Astroblastoma

Pleomorphic Adenoma Carcinoma

Carcinoma Ex Pleomorphic Adenoma

Carcinoma In Pleomorphic Adenoma

Solitary Fibrous Tumor/Hemangiopericytoma

Sft/Hpc

Cerebellum Cancer

Cerebellar Neoplasms	Cerebellar Cancer
Malignant Tumor Of Cerebellum	Malignant Neoplasm Of Cerebellum

Subependymal Glioma

Mixed Subependymoma-Ependymoma	Subependymal Astrocytoma
Who Grade I Ependymal Tumor	Glioma, Subependymal

Acute Basophilic Leukemia

Low Grade Glioma

Benign Glioma

Burkitt Lymphoma

Burkitt'S Lymphoma	BL
Burkitt Lymphoma, Somatic	Burkitt Lymphoma/Leukaemia
Burkitt'S Tumor	Burkitt'S Tumor Or Lymphoma
Malignant Lymphoma, Burkitt'S Type	Small Non-Cleaved Cell Lymphoma, Burkitt'S Type
Small Non-Cleaved Cell Lymphoma	Burkitt Tumor
Burkitts Lymphoma	Lymphoma, Small Noncleaved-Cell
Burkitt Tumour	Diffuse Small Noncleaved Malignant Burkitt Lymphoma
Malignant Burkitt Lymphoma	“Burkitt-Like” Lymphoma
Undifferentiated Burkitt Lymphoma	Small Noncleaved Cell Burkitt Lymphoma

Pilocytic Astrocytoma

Juvenile Pilocytic Astrocytoma	Grade I Astrocytic Tumor
Piloid Astrocytoma

Central Nervous System Benign Neoplasm

Benign Neoplasm Of The Central Nervous System

Salivary Gland Disease

Salivary Gland Disorders	Salivary Gland Diseases
Non-Neoplastic Salivary Gland Disease	Non-Neoplastic Salivary Gland Disorder
Disorder Of Salivary Gland	Lesion Of Salivary Gland Nos

Spinal Cord Disease

Spinal Cord Diseases	Myelopathy
Bone Marrow Diseases

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08871	MYBL1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MYBL1	VGNC	VGNC:68371
Macaca mulatta	MYBL1	VGNC	VGNC:75091
Rattus norvegicus	MYBL1	RGD	RGD:1306940
Canis familiaris	MYBL1	VGNC	VGNC:43520
Bos taurus	MYBL1	VGNC	VGNC:31778
Mus musculus	MYBL1	MGD	MGI:99925