1. Gene
  2. NDUFB4 - NADH:ubiquinone oxidoreductase subunit B4 Gene

NDUFB4 - NADH:ubiquinone oxidoreductase subunit B4 Gene

Homo sapiens

Also known as B15; CI-B15

Gene ID: 4710 | Gene type: protein coding

About NDUFB4

Cytogenetic location: 3q13.33 Genomic coordinates (GRCh38): 3:120,596,336-120,602,507 (from NCBI)

This gene has 6 transcripts (splice variants) and 227 orthologues. Ubiquitous expression in adrenal (RPKM 52.4), heart (RPKM 52.2) and 25 other tissues.

Summary

This gene encodes a non-catalytic subunit of the multisubunit NADH:ubiquinone oxidoreductase, the first Enzyme complex in the mitochondrial electron transport chain (complex I). Mammalian complex I is composed of 45 different subunits and transfers electrons from NADH to ubiquinone. [provided by RefSeq, Dec 2009]

NDUFB4 Products(2)

mRNA Protein Name
NM_001168331.2 NP_001161803.1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 isoform 2
NM_004547.6 NP_004538.2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 isoform 1

NDUFB4 Protein Structure

NDUF_B4

NDUF_B4: NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) (5 - 129)

  • 0
  • 100
  • 129 a.a.
Protein Preferred Names Protein Names

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa

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Orthologs Information

Species Symbol Source ID
Rattus norvegicus NDUFB4 RGD RGD:1307072
Felis catus NDUFB4 VGNC VGNC:102785
Canis familiaris NDUFB4 VGNC VGNC:43703
Mus musculus NDUFB4 MGD MGI:1915444
Macaca mulatta NDUFB4 VGNC VGNC:75157