NTSR1 - neurotensin receptor 1 Gene

Homo sapiens

Also known as NTR

Gene ID: 4923 | Gene type: protein coding

About NTSR1

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:62,708,836-62,762,771 (from NCBI)

This gene has 2 transcripts (splice variants), 213 orthologues and 15 paralogues. Low expression observed in reference dataset.

Summary

Neurotensin Receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008]

NTSR1 Products(1)

mRNA	Protein	Name
NM_002531.3	NP_002522.2	neurotensin receptor type 1

NTSR1 Protein Structure

7tm_1

0
100
200
300
418 a.a.

Protein Preferred Names

Protein Names

neurotensin receptor type 1

NT-R-1	NTR1
NTRH	high-affinity levocabastine-insensitive neurotensin receptor
neurotensin receptor 1 (high affinity)

Related Diseases

Diseases

Alias

Trigeminal Nerve Neoplasm

Neoplasm Of Trigeminal Nerve

Tumor Of Trigeminal Nerve

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Pancreatic Cancer

Pancreatic Carcinoma	Familial Pancreatic Carcinoma
Pancreatic Neoplasm	Carcinoma Of Pancreas
Pancreatic Carcinoma, Familial	Malignant Neoplasm Of Pancreas
Pancreatic Acinar Carcinoma	Pancreatic Tumor
Familial Pancreatic Cancer	Neoplasm Of The Pancreas
Pancreatic Carcinoma, Somatic	Pancreatic Cancer, Somatic
Ca Body Of Pancreas	Ca Head Of Pancreas
Ca Tail Of Pancreas	Malignant Neoplasm Of Body Of Pancreas
Malignant Neoplasm Of Head Of Pancreas	Malignant Neoplasm Of Tail Of Pancreas
Pancreas Neoplasm	Exocrine Cancer
Exocrine Pancreas Carcinoma	Hereditary Pancreatic Cancer
Hereditary Pancreatic Carcinoma	PNCA
Cancer Of The Pancreas	Pancreatic Cancer, Susceptibility To
Carcinoma Of Head Of Pancreas	Pancreatic Neoplasms
Pancreatic Tumors	Cancer, Pancreatic
Cancer Of Pancreas	Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Brain Stem Medulloblastoma

Jugular Foramen Meningioma

Meningioma Of The Jugular Foramen

Acute Flaccid Myelitis

Paralytic Poliomyelitis

Poliomyelitis, Paralytic

Schwannoma Of Twelfth Cranial Nerve

Hypoglossal Schwannoma

Schwannoma Of The Twelfth Cranial Nerve

Suprasellar Meningioma

Hypoglossal Nerve Disease

Hypoglossal Nerve Diseases	Disorder Of 12th Nerve
Disorder Of Hypoglossal [12th] Nerve	Disorder Of Hypoglossal Nerve
Disorder Of Xii Nerve	Disorders Of The Twelfth Cranial Nerve
Disorders Of 12th Cranial Nerve

Petrous Apex Meningioma

Meningioma Of The Petrous Ridge

Neurilemmoma Of The Fifth Cranial Nerve

Trigeminal Schwannoma

Trigeminal Neurilemmoma

Colon Adenocarcinoma

Adenocarcinoma Of Colon	Adenocarcinoma Of The Colon
Colonic Adenocarcinoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-125880	SBI-553	Modulator	99.86%	Unkown
HY-RS09638	NTSR1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09639	Ntsr1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09640	Ntsr1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	NTSR1	RGD	RGD:1306076
Canis familiaris	NTSR1	VGNC	VGNC:44014
Bos taurus	NTSR1	VGNC	VGNC:32312
Felis catus	NTSR1	VGNC	VGNC:68582
Mus musculus	NTSR1	MGD	MGI:97386
Macaca mulatta	NTSR1	VGNC	VGNC:75544
Macaca fascicularis	NTSR1	NCBI	NCBI:102115340
Others	NTSR1	NCBI

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