G0S2 - G0/G1 switch 2 Gene

Homo sapiens

Gene ID: 50486 | Gene type: protein coding

About G0S2

Cytogenetic location: 1q32.2 Genomic coordinates (GRCh38): 1:209,675,412-209,676,390 (from NCBI)

This gene has 1 transcript (splice variant) and 163 orthologues. Biased expression in fat (RPKM 569.0), bone marrow (RPKM 395.4) and 4 other tissues.

Summary

Involved in extrinsic apoptotic signaling pathway and positive regulation of extrinsic apoptotic signaling pathway. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

G0S2 Products(1)

mRNA	Protein	Name
NM_015714.4	NP_056529.1	G0/G1 switch protein 2

G0S2 Protein Structure

G0-G1_switch_2

0
103 a.a.

Protein Preferred Names

Protein Names

G0/G1 switch protein 2

G0/G1 switch regulatory protein 2

Related Diseases

Diseases

Alias

Crohn'S Colitis

Crohn Disease

Hypothalamic Neoplasm

Hypothalamic Neoplasms	Neoplasm Of The Hypothalamus
Tumor Of Hypothalamus

Diencephalic Neoplasm

Malignant Diencephalic Neoplasm	Malignant Diencephalic Tumor
Tumor Of Diencephalon

Chanarin-Dorfman Syndrome

Neutral Lipid Storage Disease	CDS
Neutral Lipid Storage Disease With Ichthyosis	Triglyceride Storage Disease With Impaired Long-Chain Fatty Acid Oxidation
Triglyceride Storage Disease With Ichthyosis	Nlsdi
Ichthyotic Neutral Lipid Storage Disease	Dorfman-Chanarin Syndrome
Dcs	Chanarin-Dorfman Disease
Ichthyosiform Erythroderma With Leukocyte Vacuolation	Lipidosis With Triglyceride Storage Disease
Disorder Of Cornification 12	Dorfman Chanarin Syndrome
Neutral Lipid Storage Disease With Ichthyotic	Dorfman-Chanarin Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-120897	NS-3-008 hydrochloride	Inhibitor	99.65%	Unkown
HY-RS05187	G0S2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	G0S2	VGNC	VGNC:29174
Felis catus	G0S2	VGNC	VGNC:107877
Mus musculus	G0S2	MGD	MGI:1316737
Macaca mulatta	G0S2	VGNC	VGNC:99957
Rattus norvegicus	G0S2	RGD	RGD:1311675

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