MED31 - mediator complex subunit 31 Gene

Homo sapiens

Also known as Soh1; CGI-125; 3110004H13Rik

Gene ID: 51003 | Gene type: protein coding

About MED31

This gene has 4 transcripts (splice variants) and 195 orthologues. Ubiquitous expression in brain (RPKM 6.0), adrenal (RPKM 4.6) and 25 other tissues.

Summary

Predicted to enable transcription coregulator activity and ubiquitin protein ligase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within limb development and negative regulation of fibroblast proliferation. Predicted to be located in nucleoplasm. Predicted to be part of core mediator complex and mediator complex. [provided by Alliance of Genome Resources, Apr 2022]

MED31 Products(1)

mRNA	Protein	Name
NM_016060.3	NP_057144.1	mediator of RNA polymerase II transcription subunit 31

MED31 Protein Structure

Med31

0
100
131 a.a.

Protein Preferred Names

Protein Names

mediator of RNA polymerase II transcription subunit 31

hSOH1

Related Diseases

Diseases

Alias

Hypermobility Of Coccyx

Coccygeal Hypermobility Syndrome

Hypermobility Of The Coccyx

Klippel-Feil Syndrome 3

Superior Mesenteric Artery Syndrome

Wilkie Syndrome	Wilkie'S Syndrome
Arteriomesenteric Duodenal Compression Syndrome	Cast Syndrome
Vascular Compression Of The Duodenum	Smas
Arteriomesenteric Compression Of Duodenojejunal Flexure

Spinal Canal Intradural Extramedullary Neoplasm

Intradural Extramedullary Spinal Tumors

Intradural Extramedullary Spinal Canal Neoplasm

Kummell'S Disease

Traumatic Spondylopathy	Kummell Disease
Kummell'S Spondylitis	Kümmelll-Verneuil Disease
Kümmell Spondylitis	Kümmell Disease
Traumatic Spondylosis

Brown-Sequard Syndrome

Brown-Squard Syndrome	Hemicord Syndrome
Hemiparaplegic Syndrome	Hemispinal Cord Syndrome
Brown-Séquard Syndrome

Plexopathy

Discitis

Urocanase Deficiency

Encephalopathy Due To Urocanase Deficiency	Urocanate Hydratase Deficiency
Urocanic Aciduria	UROCD
High Urine Urocanic Acid Levels

Scheuermann Disease

Scheuermann'S Disease	Spinal Osteochondrosis
Juvenile Osteochondrosis Of Spine	Familial Scheuermann Disease
Familial Scheuermann Juvenile Kyphosis	Familial Spinal Osteochondrosis
Scheuermann Juvenile Kyphosis	Juvenile Osteochondritis Of The Spine
Juvenile Osteochondrosis Of Scheurermann	Scheuermann'S Kyphosis
Sherman'S Disease	Juvenile Kyphosis
Scheuermann Kyphosis	[X]Spinal Osteochondrosis, Unspecified

Tarsal Tunnel Syndrome

Neuropathy Of The Posterior Tibial Nerve And Its Branches	Posterior Tibial Nerve Neuralgia
Compression Of Posterior Tibial Nerve In Tarsal Tunnel

Epidural Abscess

Abscess Epidural

Tibial Neuropathy

Posterior Tibial Neuropathy

Spondylolysis

Acquired Spondylolysis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08302	MED31 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MED31	VGNC	VGNC:99276
Macaca mulatta	MED31	VGNC	VGNC:104630
Mus musculus	MED31	MGD	MGI:1914529
Bos taurus	MED31	VGNC	VGNC:31367
Canis familiaris	MED31	VGNC	VGNC:43138
Rattus norvegicus	MED31	RGD	RGD:1309457

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