MRNIP - MRN complex interacting protein Gene

Homo sapiens

Also known as C5orf45

Gene ID: 51149 | Gene type: protein coding

About MRNIP

Cytogenetic location: 5q35.3 Genomic coordinates (GRCh38): 5:179,837,276-179,858,817 (from NCBI)

This gene has 24 transcripts (splice variants), 1 gene allele and 122 orthologues. Ubiquitous expression in endometrium (RPKM 41.9), lung (RPKM 28.1) and 25 other tissues.

Summary

Enables chromatin binding activity. Involved in several processes, including mitotic G2 DNA damage checkpoint signaling; regulation of double-strand break repair; and response to ionizing radiation. Located in nucleoplasm. Colocalizes with Mre11 complex. [provided by Alliance of Genome Resources, Apr 2022]

MRNIP Products(2)

mRNA	Protein	Name
NM_001017987.3	NP_001017987.1	MRN complex-interacting protein isoform 2
NM_016175.4	NP_057259.2	MRN complex-interacting protein isoform 1

Protein Preferred Names

Protein Names

MRN complex-interacting protein

MRN-interacting protein

Related Diseases

Diseases

Alias

Xeroderma Pigmentosum, Complementation Group B

Xeroderma Pigmentosum Group B	Xeroderma Pigmentosum, Group B
XPB	Xpbc
Xp Group B	Xp, Group B
Xeroderma Pigmentosum Complementation Group B	XP-B
Xeroderma Pigmentosum Group B With Cockayne Syndrome	Xeroderma Pigmentosum Ii
Xp2	Xp-B/Cs

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08658	MRNIP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	MRNIP	VGNC	VGNC:52861
Mus musculus	MRNIP	MGD	MGI:1915317
Felis catus	MRNIP	VGNC	VGNC:63584
Canis familiaris	MRNIP	VGNC	VGNC:56068
Macaca mulatta	MRNIP	VGNC	VGNC:84447
Rattus norvegicus	MRNIP	RGD	RGD:1564036

Name
Email *

	Sorry, but the email address you supplied was invalid.