2. Gene
  3. PLEKHO1 - pleckstrin homology domain containing O1 Gene

PLEKHO1 - pleckstrin homology domain containing O1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as JBP; CKIP1; OC120; CKIP-1

Gene ID: 51177 | Gene type: protein coding

About PLEKHO1

Cytogenetic location: 1q21.2 Genomic coordinates (GRCh38): 1:150,149,646-150,160,065 (from NCBI)

This gene has 9 transcripts (splice variants), 197 orthologues and 1 paralogue. Broad expression in testis (RPKM 30.7), appendix (RPKM 29.1) and 24 other tissues.

Summary

Predicted to act upstream of or within several processes, including lamellipodium morphogenesis; myoblast fusion; and myoblast migration. Predicted to be located in cell projection membrane; cytoplasm; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

PLEKHO1 Products(4)

mRNA Protein Name
NM_001304722.2 NP_001291651.1 pleckstrin homology domain-containing family O member 1 isoform b
NM_001304723.2 NP_001291652.1 pleckstrin homology domain-containing family O member 1 isoform b
NM_001304724.2 NP_001291653.1 pleckstrin homology domain-containing family O member 1 isoform c
NM_016274.6 NP_057358.2 pleckstrin homology domain-containing family O member 1 isoform a

PLEKHO1 Protein Structure

PH

PH: PH domain (24 - 131)

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  • 409 a.a.
Protein Preferred Names Protein Names

pleckstrin homology domain-containing family O member 1

C-Jun-binding protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10700 PLEKHO1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PLEKHO1 RGD RGD:1311487
Mus musculus PLEKHO1 MGD MGI:1914470
Canis familiaris PLEKHO1 VGNC VGNC:44687
Felis catus PLEKHO1 VGNC VGNC:80309
Bos taurus PLEKHO1 VGNC VGNC:33026
Macaca mulatta PLEKHO1 VGNC VGNC:76101